Tranmere Rovers conceded the fewest goals in League Two in 2021/2022, with 40 goals from 46 games. Exeter City and Northampton Town were next on 41.
Northampton Town, Tranmere Rovers and Exeter City were level on 0.9 a game, the fewest by any team in League Two in 2021/2022. Four teams were next on 1.0.
| Rank | Team | Goals Against |
|---|---|---|
| 1 | Tranmere Rovers | 40 |
| 2 | Exeter City | 41 |
| 3 | Northampton Town | 41 |
| 4 | Forest Green Rovers | 44 |
| 5 | Salford City | 46 |
| 6 | Leyton Orient | 47 |
| 7 | Port Vale | 48 |
| 8 | Bristol Rovers | 49 |
| 9 | Sutton United | 53 |
| 10 | Bradford City | 55 |
| 11 | Mansfield Town | 56 |
| 12 | Swindon Town | 57 |
| 13 | Barrow | 57 |
| 14 | Newport County | 58 |
| 15 | Rochdale | 59 |
| 16 | Colchester United | 60 |
| 17 | Walsall | 60 |
| 18 | Carlisle United | 62 |
| 19 | Hartlepool United | 64 |
| 20 | Crawley Town | 66 |
| 21 | Stevenage | 68 |
| 22 | Harrogate Town | 75 |
| 23 | Oldham Athletic | 75 |
| 24 | Scunthorpe United | 90 |