Ezekiel Elliott led the NFL in rushing yards in the 2018 regular season with 1,434.
Next came Saquon Barkley (1,307) and Todd Gurley (1,251) — the full top 50 is ranked below with team and position.
| Rank | Player | Team | Position | Rushing Yards |
|---|---|---|---|---|
| 1 | Ezekiel Elliott | DAL | UNK | 1,434 |
| 2 | Saquon Barkley | PHI | RB | 1,307 |
| 3 | Todd Gurley | LAR | UNK | 1,251 |
| 4 | Joe Mixon | CIN | RB | 1,168 |
| 5 | Chris Carson | SEA | UNK | 1,151 |
| 6 | Christian McCaffrey | SF | RB | 1,098 |
| 7 | Derrick Henry | BAL | RB | 1,059 |
| 8 | Adrian Peterson | WSH | UNK | 1,042 |
| 9 | Phillip Lindsay | IND | UNK | 1,037 |
| 10 | Nick Chubb | HOU | RB | 996 |
| 11 | Lamar Miller | HOU | UNK | 973 |
| 12 | James Conner | ARI | RB | 973 |
| 13 | David Johnson | HOU | UNK | 940 |
| 14 | Jordan Howard | CHI | UNK | 935 |
| 15 | Sony Michel | LAC | UNK | 931 |
| 16 | Marlon Mack | IND | UNK | 908 |
| 17 | Melvin Gordon III | BAL | UNK | 885 |
| 18 | Alvin Kamara | NO | RB | 883 |
| 19 | Peyton Barber | LV | UNK | 871 |
| 20 | Kareem Hunt | KC | RB | 824 |
| 21 | Matt Breida | NYG | UNK | 814 |
| 22 | Tevin Coleman | NYJ | UNK | 800 |
| 23 | Aaron Jones Sr. | MIN | RB | 728 |
| 24 | Doug Martin | LV | UNK | 723 |
| 25 | Frank Gore | BUF | UNK | 722 |