Simone Romagnoli, Giulio Maggiore, Alessio Iovine and Aljosa Vasic were each sent off once in the Coppa Italia in 2024/2025. Eight players were level on 1 in 2023/2024.
Simone Romagnoli of Sampdoria had the most red cards of any defender in the Coppa Italia in 2024/2025, with 1 red card from two appearances. No other defender had one.
| Rank | Player | Team | Red Cards |
|---|---|---|---|
| 1 | Simone Romagnoli | Sampdoria | 1 |
| 2 | Giulio Maggiore | Salernitana | 1 |
| 3 | Alessio Iovine | Como | 1 |
| 4 | Aljosa Vasic | Palermo | 1 |