Bobby Wagner led the NFL in tackles in the 2019 regular season with 159.
Next came Blake Martinez (155) and Jordan Hicks (149) — the full top 50 is ranked below with team and position.
| Rank | Player | Team | Position | Tackles |
|---|---|---|---|---|
| 1 | Bobby Wagner | WSH | LB | 159 |
| 2 | Blake Martinez | GB | UNK | 155 |
| 3 | Jordan Hicks | MIN | UNK | 149 |
| 4 | Budda Baker | ARI | S | 147 |
| 5 | Luke Kuechly | CAR | UNK | 144 |
| 6 | Jaylon Smith | NYG | UNK | 142 |
| 7 | Zach Cunningham | DET | LB | 142 |
| 8 | Cory Littleton | HOU | UNK | 134 |
| 9 | Todd Davis | MIN | UNK | 134 |
| 10 | Joe Schobert | PIT | UNK | 133 |
| 11 | K.J. Wright | LV | UNK | 132 |
| 12 | Eric Reid | SF | UNK | 130 |
| 13 | De'Vondre Campbell | SF | UNK | 129 |
| 14 | Jerome Baker | CLE | LB | 126 |
| 15 | Anthony Walker Jr. | MIA | LB | 124 |
| 16 | Lavonte David | TB | LB | 123 |
| 17 | Shaquille Leonard | IND | UNK | 121 |
| 18 | Fred Warner | SF | LB | 118 |
| 19 | Landon Collins | WSH | UNK | 117 |
| 20 | Tremaine Edmunds | NYG | LB | 115 |
| 21 | Shawn Williams | ATL | S | 114 |
| 22 | Logan Ryan | SF | UNK | 113 |
| 23 | Thomas Davis Sr. | LAC | UNK | 112 |
| 24 | Demario Davis | NYJ | LB | 111 |
| 25 | Rashaan Evans | ATL | UNK | 111 |