C.J. Gardner-Johnson, Justin Simmons, Minkah Fitzpatrick and Riq Woolen shared the NFL lead in interceptions in 2022 with 6.
Next came Jalen Pitre (5) and Tashaun Gipson Sr. (5) — the full top 50 is ranked below with team and position.
| Rank | Player | Team | Position | Interceptions |
|---|---|---|---|---|
| 1 | C.J. Gardner-Johnson | BUF | S | 6 |
| 2 | Justin Simmons | ATL | UNK | 6 |
| 3 | Minkah Fitzpatrick | NYJ | S | 6 |
| 4 | Riq Woolen | PHI | CB | 6 |
| 5 | Jalen Pitre | HOU | S | 5 |
| 6 | Tashaun Gipson Sr. | SF | UNK | 5 |
| 7 | Patrick Peterson | MIN | UNK | 5 |
| 8 | Harrison Smith | MIN | S | 5 |
| 9 | Jaire Alexander | PHI | CB | 5 |
| 10 | DaRon Bland | DAL | CB | 5 |
| 11 | Jalen Ramsey | PIT | CB | 4 |
| 12 | Talanoa Hufanga | DEN | S | 4 |
| 13 | Vonn Bell | CIN | UNK | 4 |
| 14 | Rasul Douglas | MIA | CB | 4 |
| 15 | Devin McCourty | NE | UNK | 4 |
| 16 | Jordan Poyer | BUF | S | 4 |
| 17 | Kevin Byard | NE | S | 4 |
| 18 | Quandre Diggs | TEN | S | 4 |
| 19 | Jonathan Jones | PHI | CB | 4 |
| 20 | Eddie Jackson | BAL | UNK | 4 |
| 21 | Marcus Williams | LAC | S | 4 |
| 22 | Levi Wallace | PIT | UNK | 4 |
| 23 | Jessie Bates III | ATL | S | 4 |
| 24 | Darrick Forrest | SF | S | 4 |
| 25 | Grant Delpit | CLE | S | 4 |