Kyle Fuller, Damontae Kazee and Xavien Howard shared the NFL lead in interceptions in 2018 with 7.
Next came Eddie Jackson (6) and Alec Ogletree (5) — the full top 50 is ranked below with team and position.
| Rank | Player | Team | Position | Interceptions |
|---|---|---|---|---|
| 1 | Kyle Fuller | CHI | UNK | 7 |
| 2 | Damontae Kazee | DAL | S | 7 |
| 3 | Xavien Howard | IND | CB | 7 |
| 4 | Eddie Jackson | BAL | UNK | 6 |
| 5 | Alec Ogletree | NYG | UNK | 5 |
| 6 | Shawn Williams | ATL | S | 5 |
| 7 | Kevin Byard | NE | S | 4 |
| 8 | Jordan Poyer | BUF | S | 4 |
| 9 | D.J. Swearinger | NO | UNK | 4 |
| 10 | Donte Jackson | LAC | CB | 4 |
| 11 | Trumaine Johnson | NYJ | UNK | 4 |
| 12 | Duron Harmon | CLE | UNK | 4 |
| 13 | Curtis Riley | NYG | UNK | 4 |
| 14 | Andrew Adams | TEN | UNK | 4 |
| 15 | Damarious Randall | CLE | UNK | 4 |
| 16 | Steven Nelson | HOU | UNK | 4 |
| 17 | John Johnson III | LAR | UNK | 4 |
| 18 | Cory Littleton | HOU | UNK | 3 |
| 19 | Derwin James Jr. | LAC | S | 3 |
| 20 | Harrison Smith | MIN | S | 3 |
| 21 | Brian Poole | ATL | UNK | 3 |
| 22 | Jonathan Jones | PHI | CB | 3 |
| 23 | Kenny Moore II | IND | CB | 3 |
| 24 | Chris Harris Jr. | LAC | UNK | 3 |
| 25 | Ha Ha Clinton-Dix | GB | UNK | 3 |