Jonathan Taylor led the NFL in touchdowns in the 2025 regular season with 20.
Next came Jahmyr Gibbs (18) and Christian McCaffrey (17) — the full top 50 is ranked below with team and position.
| Rank | Player | Team | Position | Touchdowns |
|---|---|---|---|---|
| 1 | Jonathan Taylor | IND | RB | 20 |
| 2 | Jahmyr Gibbs | DET | RB | 18 |
| 3 | Christian McCaffrey | SF | RB | 17 |
| 4 | Derrick Henry | BAL | RB | 16 |
| 5 | Josh Jacobs | GB | RB | 14 |
| 6 | James Cook III | BUF | RB | 14 |
| 7 | Davante Adams | LAR | WR | 14 |
| 8 | Javonte Williams | DAL | RB | 13 |
| 9 | Travis Etienne Jr. | NO | RB | 13 |
| 10 | Kyren Williams | LAR | RB | 13 |
| 11 | Breece Hall | NYJ | RB | 12 |
| 12 | RJ Harvey | DEN | RB | 12 |
| 13 | De'Von Achane | MIA | RB | 12 |
| 14 | Zach Charbonnet | SEA | RB | 12 |
| 15 | Dallas Goedert | PHI | TE | 11 |
| 16 | Chase Brown | CIN | RB | 11 |
| 17 | Bijan Robinson | ATL | RB | 11 |
| 18 | Puka Nacua | LAR | WR | 11 |
| 19 | Trey McBride | ARI | TE | 11 |
| 20 | Amon-Ra St. Brown | DET | WR | 11 |
| 21 | Tee Higgins | CIN | WR | 11 |
| 22 | TreVeyon Henderson | NE | RB | 10 |
| 23 | Ashton Jeanty | LV | RB | 10 |
| 24 | Jaxon Smith-Njigba | SEA | WR | 10 |
| 25 | D'Andre Swift | CHI | RB | 10 |