The Arizona Cardinals visit the Los Angeles Rams in Week 6 of the 2026 NFL season, on Sunday, October 18 at 4:05 PM ET at SoFi Stadium. Dome · Matrixturf. The Cardinals are 1-2 (4th in the NFC West), the Rams 1-2 (3rd in the NFC West). The Cardinals went 1-5 down the stretch, the Rams 3-3.
In 2026 the Cardinals scored 16.5 points per game (25th in the NFL) and allowed 22.5 (14th in the NFL); the Rams scored 17.5 (22nd in the NFL) and allowed 16.5 (8th in the NFL).
Head-to-head, the recent series reads LAR 5–1 over the last 6 meetings, at an average total of 46.3; against the spread it is LAR 4–2, and the total has gone OVER 4–2. LAR have taken 5 of the last 6 and are unbeaten at home in the series — 1 of the 6 landed inside a score.
Injury report: 15 players out and 23 questionable across the two teams — Myles Garrett (LAR DE, Injured reserve), Ronnie Rivers (LAR RB, Injured reserve), Will Johnson (ARI CB, Injured reserve) and Kitan Crawford (ARI S, Injured reserve).
Frequently asked questions
When do the Cardinals play the Rams?
Arizona Cardinals at Los Angeles Rams is Week 6 of the 2026 NFL season, kicking off on Sunday, October 18 at 4:05 PM ET at SoFi Stadium.
What is the head-to-head record between the Cardinals and the Rams?
The recent series is LAR 5–1 over the last 6 meetings — the last one finished LAR 37–20 in 2025 (Week 18), and against the spread the series is LAR 4–2.
Who is injured for Cardinals vs Rams?
69 players carry a designation: 15 out and 23 questionable, including Myles Garrett (LAR DE, Injured reserve), Ronnie Rivers (LAR RB, Injured reserve), Will Johnson (ARI CB, Injured reserve) and Kitan Crawford (ARI S, Injured reserve). The report refreshes with the data sync before game days and the model prices designations in automatically.