Los Angeles Rams vs Arizona Cardinals Prediction, Odds & Props — Week 10

The Los Angeles Rams visit the Arizona Cardinals in Week 10 of the 2026 NFL season, on Sunday, November 15 at 4:05 PM ET at State Farm Stadium. Grass. The Rams are 5-4 (2nd in the NFC West), the Cardinals 3-6 (4th in the NFC West). The Rams went 4-2 down the stretch, the Cardinals 2-4.

The market has LAR -9.5 with a total of 39.5.

In 2026 the Rams scored 23.8 points per game (13th in the NFL) and allowed 20.1 (8th in the NFL); the Cardinals scored 19.8 (26th in the NFL) and allowed 28.3 (31st in the NFL).

Head-to-head, the recent series reads LAR 4–2 over the last 6 meetings, at an average total of 46.2; against the spread it is ARI 3–3, and the total has gone OVER 4–2. LAR have taken 4 of the last 6 — 2 of the 6 landed inside a score.

Injury report: 18 players out and 27 questionable across the two teams — Puka Nacua (LAR WR, Out), Zachary Carter (ARI DT, IR, designated to return), Hunter Long (ARI TE, IR, designated to return) and Davante Adams (LAR WR, Injured reserve).

Best price across 8 sportsbooks: LAR -388 at Polymarket and ARI +410 at FanDuel on the moneyline, the spread ARI +9.5 (-102) and the total 39.5 (over -105). The Props tab prices 43 player props for this game — passing, rushing and receiving yards, receptions and anytime touchdown markets — at Bet365's lines.

All Rams v Cardinals games

• Los Angeles Rams stats, schedule and roster
• Arizona Cardinals stats, schedule and roster

LAR have taken 4 of the last 6 — 2 of the 6 landed inside a score.