The San Francisco 49ers visit the New York Giants in Week 13 of the 2026 NFL season, on Sunday, December 6 at 1:00 PM ET at MetLife Stadium. Open air · Fieldturf. The 49ers are 2-0 (1st in the NFC West), the Giants 1-1 (3rd in the NFC East). The 49ers went 4-2 down the stretch, the Giants 4-2.
In 2026 the 49ers scored 31 points per game (4th in the NFL) and allowed 10 (3rd in the NFL); the Giants scored 17 (24th in the NFL) and allowed 24 (21st in the NFL).
Head-to-head, the recent series reads SF 3–1 over the last 4 meetings, at an average total of 48.8; against the spread it is SF 3–1, and the total has gone OVER 3–1. SF have taken 3 of the last 4 but have yet to win at home in the series — 1 of the 4 landed inside a score.
Injury report: 16 players out and 32 questionable across the two teams — Demarcus Robinson (SF WR, Injured reserve), James Thompson Jr. (SF DT, Out), Romello Height (SF DE, Out) and Nick Bosa (SF DE, Out).
Frequently asked questions
When do the 49ers play the Giants?
San Francisco 49ers at New York Giants is Week 13 of the 2026 NFL season, kicking off on Sunday, December 6 at 1:00 PM ET at MetLife Stadium.
What is the head-to-head record between the 49ers and the Giants?
The recent series is SF 3–1 over the last 4 meetings — the last one finished SF 34–24 in 2025 (Week 9), and against the spread the series is SF 3–1.
Who is injured for 49ers vs Giants?
90 players carry a designation: 16 out and 32 questionable, including Demarcus Robinson (SF WR, Injured reserve), James Thompson Jr. (SF DT, Out), Romello Height (SF DE, Out) and Nick Bosa (SF DE, Out). The report refreshes with the data sync before game days and the model prices designations in automatically.