The Minnesota Vikings visit the San Francisco 49ers in Week 11 of the 2026 NFL season, on Sunday, November 22 at 8:20 PM ET at Estadio Banorte. Open air · Grass. The Vikings are 2-0 (1st in the NFC North), the 49ers 2-0 (1st in the NFC West). The Vikings went 6-0 down the stretch, the 49ers 4-2.
In 2026 the Vikings scored 24 points per game (14th in the NFL) and allowed 12.5 (4th in the NFL); the 49ers scored 31 (4th in the NFL) and allowed 10 (3rd in the NFL).
Head-to-head, the recent series reads MIN 3–2 over the last 5 meetings, at an average total of 43.2; against the spread it is MIN 3–2, and the total has gone UNDER 4–1. MIN have taken 3 of the last 5 and are unbeaten at home in the series — 4 of the 5 landed inside a score.
Injury report: 21 players out and 27 questionable across the two teams — Nick Samac (MIN C, Injured reserve), Demarcus Robinson (SF WR, Injured reserve), James Thompson Jr. (SF DT, Out) and Brett Thorson (MIN P, Out).
Frequently asked questions
When do the Vikings play the 49ers?
Minnesota Vikings at San Francisco 49ers is Week 11 of the 2026 NFL season, kicking off on Sunday, November 22 at 8:20 PM ET at Estadio Banorte.
What is the head-to-head record between the Vikings and the 49ers?
The recent series is MIN 3–2 over the last 5 meetings — the last one finished MIN 23–17 in 2024 (Week 2), and against the spread the series is MIN 3–2.
Who is injured for Vikings vs 49ers?
89 players carry a designation: 21 out and 27 questionable, including Nick Samac (MIN C, Injured reserve), Demarcus Robinson (SF WR, Injured reserve), James Thompson Jr. (SF DT, Out) and Brett Thorson (MIN P, Out). The report refreshes with the data sync before game days and the model prices designations in automatically.