Carolina Panthers vs New Orleans Saints Prediction, Odds & Props — Week 10

The Carolina Panthers visit the New Orleans Saints in Week 10 of the 2026 NFL season, on Sunday, November 15 at 1:00 PM ET at Caesars Superdome. Dome · Sportturf. The Panthers are 3-5 (2nd in the NFC South), the Saints 3-5 (1st in the NFC South). The Panthers went 2-4 down the stretch, the Saints 2-4.

The market has NO -2.5 with a total of 48.5.

In 2026 the Panthers scored 24.9 points per game (11th in the NFL) and allowed 27.4 (29th in the NFL); the Saints scored 23.1 (15th in the NFL) and allowed 27 (27th in the NFL).

Head-to-head, the recent series reads NO 5–1 over the last 6 meetings, at an average total of 39; against the spread it is NO 4–1, and the total has gone UNDER 4–2. NO have taken 5 of the last 6 and are unbeaten at home in the series — 3 of the 6 landed inside a score.

Injury report: 17 players out and 16 questionable across the two teams — Damien Lewis (CAR G, Out), Will Lee III (CAR CB, Out), Jaelan Phillips (CAR LB, Out) and Travis Etienne Jr. (NO RB, IR, designated to return).

Best price across 8 sportsbooks: CAR +125 at Kalshi and NO -125 at Kalshi on the moneyline, the spread NO -2.5 (+102) and the total 48.5 (over +100). The Props tab prices 57 player props for this game — passing, rushing and receiving yards, receptions and anytime touchdown markets — at Bet365's lines.

All Panthers v Saints games

Carolina Panthers vs New Orleans Saints: team comparison (2026 season, NFL rank in brackets)
Carolina PanthersNew Orleans Saints
Record3-53-5
Division2nd NFC S1st NFC S
Last six resultsL W W L L LL L L W L W
Points / G24.9 (11th)23.1 (15th)
Total Yds / G381.8 (8th)343.5 (16th)
Yards / Play5.8 (10th)5.2 (24th)
Pass Yds / G280.5 (4th)248.3 (13th)
Rush Yds / G101.3 (23rd)95.3 (26th)
3rd Down %37.7% (19th)43.5% (7th)
1st Downs / G22.0 (7th)20.5 (11th)
Turnover Diff-1 (19th)-6 (28th)
Pts Allowed / G27.4 (29th)27 (27th)
Yds Allowed / G355.1 (20th)389.5 (30th)
Pass Yds Allowed221.8 (8th)255.6 (28th)
Rush Yds Allowed133.4 (28th)133.9 (29th)
Sacks12 (32nd)23 (11th)
  • Carolina Panthers stats, schedule and roster
  • New Orleans Saints stats, schedule and roster
Best odds on the game
BetPriceSportsbook
Carolina Panthers moneyline+125Kalshi
New Orleans Saints moneyline-125Kalshi
New Orleans Saints -2.5+102Kalshi
Over 48.5 points+100Polymarket
Carolina Panthers vs New Orleans Saints injury report
PlayerTeamPositionStatusInjury
Damien LewisCARGOutKnee
CJ DonaldsonNORBQuestionableShoulder
Noah FantNOTEQuestionableBack
Christen MillerNODTQuestionableKnee
Kelvin Banks Jr.NOOTQuestionableAnkle
David EdwardsNOGQuestionableKnee
Martin Emerson Jr.NOCBQuestionableShin
Bobby OkerekeCARLBQuestionableFoot
Will Lee IIICARCBOutHamstring
Jaelan PhillipsCARLBOutHamstring
Alvin KamaraNORBQuestionableNot injury related - resting player
Travis Etienne Jr.NORBIR, designated to returnHamstring
Jonathon BrooksCARRBIR, designated to returnGroin
Mike JacksonCARCBIR, designated to returnGroin
Xavier LegetteCARWRIR, designated to returnKnee
Claudin CherelusCARLBQuestionableShoulder
Erik McCoyNOCDoubtfulBiceps
Jaycee HornCARCBInjured reserveQuadriceps
Brady ChristensenCARGIR, designated to returnHamstring
Akayleb EvansCARCBInjured reserveTriceps
Taylor MotonCAROTInjured reserveNot injury related - resting player
Thomas IncoomCARLBInjured reserveCalf
Cam JacksonCARDTInjured reserveKnee
Ikem EkwonuCAROTReserve/PUPKnee
Dillon RadunzNOGInjured reserve
Mason TiptonNOWRReserve/PUPLeg
Moliki MatavaoNOTEInjured reserveKnee
Ty ChandlerNORBInjured reserveKnee
Rejzohn WrightNOCBInjured reserveHip
Bryan BreseeNODTInjured reserve
Chris Brazzell IICARWRInjured reserve
Nic ScourtonCARLBInjured reserveKnee
Nick SaldiveriNOOTReserve/PUPKnee
Dan ChisenaCARWRInjured Reserve
Popo AumavaeCARDTInjured Reserve
Tyrek FunderburkCARCBInjured Reserve
Corey ThorntonCARCBInjured Reserve
Ryan HayesCAROTInjured Reserve
Torricelli Simpkins IIINOGQuestionable
Will ClappNOCInjured Reserve
Taysom HillNOQBQuestionable
Devin NealNORBInjured Reserve
Jack StollNOTEInjured Reserve
Ja'Lynn PolkNOWRQuestionable
Trey PalmerNOWRQuestionable
Landon YoungNOOTInjured Reserve
Barry WesleyNOOTInjured Reserve
Keeshawn SilverNODTOut
Zxavian HarrisNODTOut
Michael HeldmanNOLBInjured Reserve
Brock RechsteinerNOWRSUSP
Brien Taylor Jr.NODTQuestionable
David Long Jr.NOCBInjured Reserve
Jordyn TysonNOWRQuestionable
Lorenzo Styles Jr.NOSQuestionable
Player props: Bet365 lines
PlayerMarketLineOverUnder
Bryce YoungPassing Yards256.5-116-116
Tyler ShoughPassing Yards256.5-116-116
Chuba HubbardRushing Yards72.5-116-116
Chris OlaveReceiving Yards68.5-116-116
Tetairoa McMillanReceiving Yards65.5-116-116
Jalen CokerReceiving Yards50.5-116-116
Jordyn TysonReceiving Yards41.5-116-116
Devaughn VeleReceiving Yards34.5-116-116
Darren WallerReceiving Yards28.5-116-116
Juwan JohnsonReceiving Yards23.5-116-116
Tommy TrembleReceiving Yards21.5-116-116
Chuba HubbardReceiving Yards18.5-116-116
Chuba HubbardRush Attempts17.5-132+100
Tyler ShoughRushing Yards16.5-116-116
John Metchie IIIReceiving Yards15.5-116-116
Mitchell EvansReceiving Yards9.5-116-116
Noah FantReceiving Yards9.5-116-116
Bryce YoungRushing Yards8.5-116-116
Chris OlaveReceptions5.5-152+120
Tetairoa McMillanReceptions5.5-116-116
Tyler ShoughRush Attempts4.5-116-116
Jordyn TysonReceptions4.5-111-120
Jalen CokerReceptions4.5+115-147
Devaughn VeleReceptions3.5+120-152
Chuba HubbardReceptions2.5-156+122
Darren WallerReceptions2.5-147+115
Tommy TrembleReceptions2.5-120-111
Juwan JohnsonReceptions2.5-116-116
Bryce YoungRush Attempts2.5+105-135
John Metchie IIIReceptions1.5-132+100
Bryce YoungPassing TDs1.5-116-116
Tyler ShoughPassing TDs1.5-116-116
Mitchell EvansReceptions1.5+125-161
Noah FantReceptions1.5+125-161
Chuba HubbardAnytime TD-161
Audric EstimeAnytime TD+120
Tetairoa McMillanAnytime TD+125
Chris OlaveAnytime TD+130
Alvin KamaraAnytime TD+160
Jalen CokerAnytime TD+185

NO have taken 5 of the last 6 and are unbeaten at home in the series — 3 of the 6 landed inside a score.

Recent meetings
GameWinnerScoreVenue
2025 Week 15NO20–17Caesars Superdome
2025 Week 10NO17–7Bank of America Stadium
2024 Week 9CAR23–22Bank of America Stadium
2024 Week 1NO47–10Caesars Superdome
2023 Week 14NO28–6Caesars Superdome
2023 Week 2NO20–17Bank of America Stadium

Frequently asked questions

When do the Panthers play the Saints?

Carolina Panthers at New Orleans Saints is Week 10 of the 2026 NFL season, kicking off on Sunday, November 15 at 1:00 PM ET at Caesars Superdome.

Who is favoured, the Panthers or the Saints?

The market makes it NO -2.5 with a total of 48.5.

What is the head-to-head record between the Panthers and the Saints?

The recent series is NO 5–1 over the last 6 meetings — the last one finished NO 20–17 in 2025 (Week 15), and against the spread the series is NO 4–1.

Who is injured for Panthers vs Saints?

55 players carry a designation: 17 out and 16 questionable, including Damien Lewis (CAR G, Out), Will Lee III (CAR CB, Out), Jaelan Phillips (CAR LB, Out) and Travis Etienne Jr. (NO RB, IR, designated to return).

What are the odds for Panthers vs Saints?

The best prices on Statz NFL are CAR +125 at Kalshi and NO -125 at Kalshi on the moneyline, the spread NO -2.5 (+102) and the total 48.5 (over +100), compared across 8 sportsbooks. Every price links out to the book.

Which player props are available for Panthers vs Saints?

57 player props for this game — passing, rushing and receiving yards, receptions and anytime touchdown markets at Bet365's lines. The Statz model projects every one and rates it at the quoted price; the ratings are part of NFL Pro.

Panthers v Saints: teams and standings

  • Carolina Panthers
  • Carolina Panthers Stats
  • New Orleans Saints
  • New Orleans Saints Stats
  • NFC South Standings
  • NFC Standings
  • NFL Power Rankings this week

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