The Detroit Lions visit the Carolina Panthers in Week 4 of the 2026 NFL season, on Sunday, October 4 at 8:20 PM ET at Bank of America Stadium. Open air · Grass. The Lions are 1-1 (3rd in the NFC North), the Panthers 1-1 (2nd in the NFC South). The Lions went 3-3 down the stretch, the Panthers 1-5.
In 2026 the Lions scored 31 points per game (5th in the NFL) and allowed 35.5 (31st in the NFL); the Panthers scored 35.5 (2nd in the NFL) and allowed 31 (30th in the NFL).
Head-to-head, the recent series reads CAR 2–2 over the last 4 meetings, at an average total of 46.3; against the spread it is CAR 2–2, and the total has gone OVER 2–2. The last 4 meetings are split 2–2 and are unbeaten at home in the series — 1 of the 4 landed inside a score.
Injury report: 17 players out and 18 questionable across the two teams — Thomas Harper (DET S, Injured reserve), Claudin Cherelus (CAR LB, Injured reserve), Ben Bartch (DET G, Out) and Nick Scott (CAR S, Out).
Frequently asked questions
When do the Lions play the Panthers?
Detroit Lions at Carolina Panthers is Week 4 of the 2026 NFL season, kicking off on Sunday, October 4 at 8:20 PM ET at Bank of America Stadium.
What is the head-to-head record between the Lions and the Panthers?
The recent series is CAR 2–2 over the last 4 meetings — the last one finished DET 42–24 in 2023 (Week 5), and against the spread the series is CAR 2–2.
Who is injured for Lions vs Panthers?
67 players carry a designation: 17 out and 18 questionable, including Thomas Harper (DET S, Injured reserve), Claudin Cherelus (CAR LB, Injured reserve), Ben Bartch (DET G, Out) and Nick Scott (CAR S, Out). The report refreshes with the data sync before game days and the model prices designations in automatically.