Buffalo Bills vs Cincinnati Bengals Prediction, Odds & Props

Buffalo Bills vs Cincinnati Bengals Prediction, Odds & Props — Week 17

The Buffalo Bills visit the Cincinnati Bengals in Week 17 of the 2022 NFL season, on Monday, January 2 at 8:30 PM ET at Paycor Stadium. The Bills are 13-3 (1st in the AFC East), the Bengals 12-4 (1st in the AFC North). The Bills went 5-1 down the stretch, the Bengals 5-1.

In 2022 the Bills scored 28.4 points per game (2nd in the NFL) and allowed 17.9 (2nd in the NFL); the Bengals scored 26.1 (7th in the NFL) and allowed 20.1 (5th in the NFL).

Head-to-head, the recent series reads CIN 2–2 over the last 4 meetings, at an average total of 47.5; against the spread it is CIN 4–0, and the total has gone UNDER 3–1. The last 4 meetings are split 2–2 — 3 of the 4 landed inside a score.

Injury report: 1 player out and 10 questionable across the two teams — Joshua Palmer (BUF WR, Injured reserve), Tyrell Shavers (BUF WR, Reserve/PUP), Andrei Iosivas (CIN WR, Injured reserve) and Jordan Hancock (BUF CB, IR, designated to return).

All Bills v Bengals games

Buffalo Bills vs Cincinnati Bengals: team comparison (2022 season, NFL rank in brackets)
	Buffalo Bills	Cincinnati Bengals
Record	13-3	12-4
Division	1st AFC E	1st AFC N
Last six results	W W W W W L	W W W W W L
Points / G	28.4 (2nd)	26.1 (7th)
Total Yds / G	407.7 (2nd)	378 (7th)
Yards / Play	6.3 (3rd)	5.7 (12th)
Pass Yds / G	268.2 (7th)	282.5 (3rd)
Rush Yds / G	139.5 (7th)	95.5 (29th)
3rd Down %	50.3% (1st)	46.1% (3rd)
1st Downs / G	22.9 (2nd)	22.3 (5th)
Turnover Diff	0 (15th)	+6 (6th)
Pts Allowed / G	17.9 (2nd)	20.1 (5th)
Yds Allowed / G	337.1 (7th)	345.9 (12th)
Pass Yds Allowed	232.6 (16th)	239.3 (19th)
Rush Yds Allowed	104.6 (5th)	106.6 (7th)
Sacks	40 (14th)	30 (29th)

Buffalo Bills vs Cincinnati Bengals injury report
Player	Team	Position	Status	Injury
Kyle Dugger	CIN	S	Questionable	Quadricep
Dion Dawkins	BUF	OT	Questionable	Rib
Greg Gaines	BUF	DT	Questionable	Calf
DJ Turner II	CIN	CB	Questionable	Heel
Christian Benford	BUF	CB	Questionable	Wrist
Dylan Fairchild	CIN	G	Questionable
Spencer Brown	BUF	OT	Questionable	Ankle
Connor McGovern	BUF	C	Questionable	Neck
Dalton Kincaid	BUF	TE	Questionable	Ankle
Joshua Palmer	BUF	WR	Injured reserve	Hamstring
Alec Anderson	BUF	OT	Questionable	Ankle
Tyrell Shavers	BUF	WR	Reserve/PUP	Knee
Andrei Iosivas	CIN	WR	Injured reserve	Thumb
Jordan Hancock	BUF	CB	IR, designated to return	Hamstring
Cashius Howell	CIN	DE	Injured reserve	Wrist
Erick All Jr.	CIN	TE	Injured reserve
Josh Kattus	CIN	TE	Out	Undisclosed
Tanner Hudson	CIN	TE	Injured reserve	Pectoral
Swayze Bozeman	CIN	LB	Injured reserve	Groin
Jalen Davis	CIN	CB	Injured reserve	Hamstring
Dorian Strong	BUF	CB	Reserve/NFI
Zane Durant	BUF	DT	IR, designated to return
Brian Parker II	CIN	OT	IR, designated to return
Ja'Sir Taylor	CIN	CB	IR, designated to return	Undisclosed

The last 4 meetings are split 2–2 — 3 of the 4 landed inside a score.

Recent meetings
Game	Winner	Score	Venue
2025 Week 14	BUF	39–34	Highmark Stadium
2023 Week 9	CIN	24–18	Paycor Stadium
2022 DIV	CIN	27–10	Highmark Stadium
2019 Week 3	BUF	21–17	Highmark Stadium

Frequently asked questions

When do the Bills play the Bengals?

Buffalo Bills at Cincinnati Bengals is Week 17 of the 2022 NFL season, kicking off on Monday, January 2 at 8:30 PM ET at Paycor Stadium.

What is the head-to-head record between the Bills and the Bengals?

The recent series is CIN 2–2 over the last 4 meetings — the last one finished BUF 39–34 in 2025 (Week 14), and against the spread the series is CIN 4–0.

Who is injured for Bills vs Bengals?

24 players carry a designation: 1 out and 10 questionable, including Joshua Palmer (BUF WR, Injured reserve), Tyrell Shavers (BUF WR, Reserve/PUP), Andrei Iosivas (CIN WR, Injured reserve) and Jordan Hancock (BUF CB, IR, designated to return).