Jacksonville Jaguars vs Indianapolis Colts Prediction, Odds & Props — Week 18

The Jacksonville Jaguars visit the Indianapolis Colts in Week 18 of the 2026 NFL season, on Sunday, January 10 at 12:00 AM ET at Lucas Oil Stadium. Fieldturf. The Jaguars are 6-2 (1st in the AFC South), the Colts 2-7 (3rd in the AFC South). The Jaguars went 5-1 down the stretch, the Colts 1-5.

In 2026 the Jaguars scored 28.6 points per game (4th in the NFL) and allowed 15.1 (2nd in the NFL); the Colts scored 20.4 (24th in the NFL) and allowed 27.7 (30th in the NFL).

Head-to-head, the recent series reads JAX 5–1 over the last 6 meetings, at an average total of 53.5; against the spread it is JAX 5–1, and the total has gone OVER 5–1. JAX have taken 5 of the last 6 — 3 of the 6 landed inside a score.

Injury report: 14 players out and 7 questionable across the two teams — Jalen Travis (IND OT, Doubtful), Cam'Ron Silmon-Craig (JAX S, Out), Alec Pierce (IND WR, Injured reserve) and Eric Murray (JAX S, Injured reserve).

All Jaguars v Colts games

Jacksonville Jaguars vs Indianapolis Colts: team comparison (2026 season, NFL rank in brackets)
Jacksonville JaguarsIndianapolis Colts
Record6-22-7
Division1st AFC S3rd AFC S
Last six resultsW W W L W WW L L L L L
Points / G28.6 (4th)20.4 (24th)
Total Yds / G359.6 (12th)307.4 (27th)
Yards / Play6.1 (6th)4.8 (31st)
Pass Yds / G242.5 (15th)192.2 (27th)
Rush Yds / G117.1 (14th)115.2 (15th)
3rd Down %46.4% (3rd)36.9% (22nd)
1st Downs / G20.3 (13th)18.6 (19th)
Turnover Diff+9 (1st)-11 (32nd)
Pts Allowed / G15.1 (2nd)27.7 (30th)
Yds Allowed / G327.6 (10th)375.3 (26th)
Pass Yds Allowed238.4 (18th)238.3 (17th)
Rush Yds Allowed89.3 (5th)137 (30th)
Sacks16 (25th)19 (16th)
  • Jacksonville Jaguars stats, schedule and roster
  • Indianapolis Colts stats, schedule and roster
Jacksonville Jaguars vs Indianapolis Colts injury report
PlayerTeamPositionStatusInjury
Jalen TravisINDOTDoubtfulThumb
Justin WalleyINDCBQuestionableKnee
Akeem Davis-GaitherINDLBQuestionableKnee
A.J. HaulcyINDSQuestionableAnkle
Mo Alie-CoxINDTEQuestionableIllness
Jaylon CarliesINDLBQuestionableRibs
Cam'Ron Silmon-CraigJAXSOutInactive
Alec PierceINDWRInjured reserveHeel
Eric MurrayJAXSInjured reserveElbow
DaVon HamiltonJAXDTInjured reserveKnee
Cam Taylor-BrittINDCBInjured reserve
Anton HarrisonJAXOTInjured reserveElbow
Arden KeyINDDEInjured reserveHamstring
Caleb RansawJAXSInjured reserveKnee
Micheal ClemonsINDDEInjured reserveToe
B.J. Green IIJAXDEInjured reserveElbow
Carson TowtINDTEInjured reserve
Sean McKeonINDTEQuestionable
Sam MustipherJAXCInjured reserveUndisclosed
Patrick MekariJAXGIR, designated to returnBack
D.J. MontgomeryINDWRInjured reserveAbdomen
Zach DurfeeJAXDEIR, designated to returnUpper body
Devon MarshallJAXCBQuestionableUndisclosed
Cameron MitchellINDCBInjured reserve
Jared BartlettJAXLBInjured reserve
Garrett DiGiorgioJAXOTInjured reserve
Parker HughesJAXLBInjured reserve
Cooper HodgesJAXOTOut
Joshua CephusJAXWRInjured Reserve
Keivie RoseJAXDTInjured Reserve
Christian BraswellJAXCBInjured Reserve
Travis HunterJAXWRInjured Reserve
Jalen McLeodJAXLBInjured Reserve
Jamal HillJAXLBOut
Jack WilsonINDOTInjured Reserve
Braden SmithINDOTInjured Reserve
Coleman OwenINDWRInjured Reserve
Jacob PhillipsINDLBInjured Reserve
Chris LammonsINDCBInjured Reserve
Salvon AhmedINDRBInjured Reserve

JAX have taken 5 of the last 6 — 3 of the 6 landed inside a score.

Recent meetings
GameWinnerScoreVenue
2026 Week 8JAX42–7EverBank Stadium
2025 Week 17JAX23–17Lucas Oil Stadium
2025 Week 14JAX36–19EverBank Stadium
2024 Week 18IND26–23Lucas Oil Stadium
2024 Week 5JAX37–34EverBank Stadium
2023 Week 6JAX37–20EverBank Stadium

Frequently asked questions

When do the Jaguars play the Colts?

Jacksonville Jaguars at Indianapolis Colts is Week 18 of the 2026 NFL season, kicking off on Sunday, January 10 at 12:00 AM ET at Lucas Oil Stadium.

What is the head-to-head record between the Jaguars and the Colts?

The recent series is JAX 5–1 over the last 6 meetings — the last one finished JAX 42–7 in 2026 (Week 8), and against the spread the series is JAX 5–1.

Who is injured for Jaguars vs Colts?

40 players carry a designation: 14 out and 7 questionable, including Jalen Travis (IND OT, Doubtful), Cam'Ron Silmon-Craig (JAX S, Out), Alec Pierce (IND WR, Injured reserve) and Eric Murray (JAX S, Injured reserve).

Jaguars v Colts: teams and standings

  • Jacksonville Jaguars
  • Jacksonville Jaguars Stats
  • Indianapolis Colts
  • Indianapolis Colts Stats
  • AFC South Standings
  • AFC Standings
  • NFL Power Rankings this week

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