The Arizona Cardinals visit the New Orleans Saints in Week 16 of the 2026 NFL season, on Sunday, December 27 at 1:00 PM ET at Caesars Superdome. Dome · Sportturf. The Cardinals are 1-1 (4th in the NFC West), the Saints 1-1 (1st in the NFC South). The Cardinals went 1-5 down the stretch, the Saints 4-2.
In 2026 the Cardinals scored 16.5 points per game (25th in the NFL) and allowed 22.5 (14th in the NFL); the Saints scored 27 (9th in the NFL) and allowed 24 (19th in the NFL).
Head-to-head, the recent series reads ARI 2–1 over the last 3 meetings, at an average total of 49.7; against the spread it is ARI 2–1, and the total has gone UNDER 2–1. ARI have taken 2 of the last 3 — 2 of the 3 landed inside a score.
Injury report: 21 players out and 32 questionable across the two teams — Kelvin Banks Jr. (NO OT, Injured reserve), Dadrion Taylor-Demerson (ARI S, Out), Christen Miller (NO DT, Out) and Barion Brown (NO WR, Out).
Frequently asked questions
When do the Cardinals play the Saints?
Arizona Cardinals at New Orleans Saints is Week 16 of the 2026 NFL season, kicking off on Sunday, December 27 at 1:00 PM ET at Caesars Superdome.
What is the head-to-head record between the Cardinals and the Saints?
The recent series is ARI 2–1 over the last 3 meetings — the last one finished ARI 20–13 in 2025 (Week 1), and against the spread the series is ARI 2–1.
Who is injured for Cardinals vs Saints?
86 players carry a designation: 21 out and 32 questionable, including Kelvin Banks Jr. (NO OT, Injured reserve), Dadrion Taylor-Demerson (ARI S, Out), Christen Miller (NO DT, Out) and Barion Brown (NO WR, Out). The report refreshes with the data sync before game days and the model prices designations in automatically.