Carolina Panthers vs Pittsburgh Steelers Prediction, Odds & Props — Week 16

The Carolina Panthers visit the Pittsburgh Steelers in Week 16 of the 2026 NFL season, on Sunday, December 27 at 12:00 AM ET at Acrisure Stadium. Open air · Grass. The Panthers are 3-5 (2nd in the NFC South), the Steelers 6-2 (1st in the AFC North). The Panthers went 2-4 down the stretch, the Steelers 5-1.

In 2026 the Panthers scored 24.9 points per game (11th in the NFL) and allowed 27.4 (29th in the NFL); the Steelers scored 22.5 (17th in the NFL) and allowed 18 (5th in the NFL).

Head-to-head, the recent series reads PIT 2–0 over the last 2 meetings, at an average total of 56.5; against the spread it is PIT 2–0, and the total has gone OVER 2–0. PIT have won all 2 recent meetings — 1 of the 2 landed inside a score.

Injury report: 21 players out and 5 questionable across the two teams — Brandin Echols (PIT CB, Out), Doneiko Slaughter (PIT CB, Out), Damien Lewis (CAR G, Out) and Ben Skowronek (PIT WR, Out).

All Panthers v Steelers games

Carolina Panthers vs Pittsburgh Steelers: team comparison (2026 season, NFL rank in brackets)
Carolina PanthersPittsburgh Steelers
Record3-56-2
Division2nd NFC S1st AFC N
Last six resultsL W W L L LW L W W W W
Points / G24.9 (11th)22.5 (17th)
Total Yds / G381.8 (8th)351.8 (14th)
Yards / Play5.8 (10th)5.6 (17th)
Pass Yds / G280.5 (4th)233.9 (17th)
Rush Yds / G101.3 (23rd)117.9 (12th)
3rd Down %37.7% (19th)37.9% (16th)
1st Downs / G22.0 (7th)19.5 (18th)
Turnover Diff-1 (19th)+5 (5th)
Pts Allowed / G27.4 (29th)18 (5th)
Yds Allowed / G355.1 (20th)325.9 (8th)
Pass Yds Allowed221.8 (8th)242 (22nd)
Rush Yds Allowed133.4 (28th)83.9 (3rd)
Sacks12 (32nd)26 (6th)
  • Carolina Panthers stats, schedule and roster
  • Pittsburgh Steelers stats, schedule and roster
Carolina Panthers vs Pittsburgh Steelers injury report
PlayerTeamPositionStatusInjury
Brandin EcholsPITCBOutHamstring
Doneiko SlaughterPITCBOutHamstring
Damien LewisCARGOutKnee
Ben SkowronekPITWROutCalf
DeShon ElliottPITSQuestionableAnkle
Bobby OkerekeCARLBQuestionableFoot
Will Lee IIICARCBOutHamstring
Jaelan PhillipsCARLBOutHamstring
Derrick HarmonPITDTIR, designated to returnFoot
Michael Pittman Jr.PITWRInjured reserveFoot
Jonathon BrooksCARRBIR, designated to returnGroin
Mike JacksonCARCBIR, designated to returnGroin
Xavier LegetteCARWRIR, designated to returnKnee
Claudin CherelusCARLBQuestionableShoulder
Jaycee HornCARCBInjured reserveQuadriceps
Brady ChristensenCARGIR, designated to returnHamstring
Akayleb EvansCARCBInjured reserveTriceps
Taylor MotonCAROTInjured reserveNot injury related - resting player
Thomas IncoomCARLBInjured reserveCalf
Sebastian Joseph-DayPITDTInjured reserveTriceps
Roman WilsonPITWRInjured reserveFinger
Cam JacksonCARDTInjured reserveKnee
Ikem EkwonuCAROTReserve/PUPKnee
Gennings DunkerPITGInjured reserveKnee
Max HurlemanPITRBOutUndisclosed
Jack DriscollPITOTIR, designated to returnUndisclosed
Donte KentPITCBOut
Cole BurgessPITWRInjured reserve
Logan LeePITDTInjured reserve
Chris Brazzell IICARWRInjured reserve
Nic ScourtonCARLBInjured reserveKnee
Daequan HardyPITCBInjured reserveUndisclosed
Calvin AndersonPITOTInjured Reserve
Donald Parham Jr.PITTEInjured Reserve
Daniel EkualePITDTInjured Reserve
Cory Trice Jr.PITCBQuestionable
Jacob SladePITDTInjured Reserve
Miles KillebrewPITSInjured Reserve
Skylar ThompsonPITQBInjured Reserve
Isaiahh LoudermilkPITDTInjured Reserve
Rico DowdlePITRBQuestionable
Kevin Jobity Jr.PITDTOut
Dan ChisenaCARWRInjured Reserve
Popo AumavaeCARDTInjured Reserve
Tyrek FunderburkCARCBInjured Reserve
Corey ThorntonCARCBInjured Reserve
Ryan HayesCAROTInjured Reserve

PIT have won all 2 recent meetings — 1 of the 2 landed inside a score.

Recent meetings
GameWinnerScoreVenue
2022 Week 15PIT24–16Bank of America Stadium
2018 Week 10PIT52–21Acrisure Stadium

Frequently asked questions

When do the Panthers play the Steelers?

Carolina Panthers at Pittsburgh Steelers is Week 16 of the 2026 NFL season, kicking off on Sunday, December 27 at 12:00 AM ET at Acrisure Stadium.

What is the head-to-head record between the Panthers and the Steelers?

The recent series is PIT 2–0 over the last 2 meetings — the last one finished PIT 24–16 in 2022 (Week 15), and against the spread the series is PIT 2–0.

Who is injured for Panthers vs Steelers?

47 players carry a designation: 21 out and 5 questionable, including Brandin Echols (PIT CB, Out), Doneiko Slaughter (PIT CB, Out), Damien Lewis (CAR G, Out) and Ben Skowronek (PIT WR, Out).

Panthers v Steelers: teams and standings

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