New York Giants vs Indianapolis Colts Prediction, Odds & Props — Week 12

The New York Giants visit the Indianapolis Colts in Week 12 of the 2026 NFL season, on Sunday, November 29 at 1:00 PM ET at Lucas Oil Stadium. Fieldturf. The Giants are 5-2-1 (1st in the NFC East), the Colts 2-7 (3rd in the AFC South). The Giants went 4-1 down the stretch, the Colts 1-5.

In 2026 the Giants scored 22.8 points per game (16th in the NFL) and allowed 21.5 (12th in the NFL); the Colts scored 20.4 (24th in the NFL) and allowed 27.7 (30th in the NFL).

Head-to-head, the recent series reads NYG 2–1 over the last 3 meetings, at an average total of 60.3; against the spread it is NYG 3–0, and the total has gone OVER 3–0. NYG have taken 2 of the last 3 — 1 of the 3 landed inside a score.

Injury report: 11 players out and 16 questionable across the two teams — Cam Skattebo (NYG RB, Out), Jalen Travis (IND OT, Doubtful), Alec Pierce (IND WR, Injured reserve) and Cam Taylor-Britt (IND CB, Injured reserve).

All Giants v Colts games

New York Giants vs Indianapolis Colts: team comparison (2026 season, NFL rank in brackets)
New York GiantsIndianapolis Colts
Record5-2-12-7
Division1st NFC E3rd AFC S
Last six resultsW W T L W WW L L L L L
Points / G22.8 (16th)20.4 (24th)
Total Yds / G349.6 (15th)307.4 (27th)
Yards / Play5.3 (23rd)4.8 (31st)
Pass Yds / G237.5 (16th)192.2 (27th)
Rush Yds / G112.1 (17th)115.2 (15th)
3rd Down %40.4% (12th)36.9% (22nd)
1st Downs / G20.3 (14th)18.6 (19th)
Turnover Diff-2 (23rd)-11 (32nd)
Pts Allowed / G21.5 (12th)27.7 (30th)
Yds Allowed / G312.9 (6th)375.3 (26th)
Pass Yds Allowed189.3 (3rd)238.3 (17th)
Rush Yds Allowed123.6 (21st)137 (30th)
Sacks16 (27th)19 (16th)
  • New York Giants stats, schedule and roster
  • Indianapolis Colts stats, schedule and roster
New York Giants vs Indianapolis Colts injury report
PlayerTeamPositionStatusInjury
Colton HoodNYGCBQuestionableFinger
J.J. McCarthyNYGQBQuestionableHip
Cam SkatteboNYGRBOutHamstring
Jalen TravisINDOTDoubtfulThumb
Justin WalleyINDCBQuestionableKnee
Akeem Davis-GaitherINDLBQuestionableKnee
A.J. HaulcyINDSQuestionableAnkle
Abdul CarterNYGLBQuestionableKnee
Malik HarrisonNYGLBQuestionableGroin
Mo Alie-CoxINDTEQuestionableIllness
Jaylon CarliesINDLBQuestionableRibs
Alec PierceINDWRInjured reserveHeel
Cam Taylor-BrittINDCBInjured reserve
Tyrone Tracy Jr.NYGRBInjured reserveKnee
Tremaine EdmundsNYGLBInjured reserveShoulder
Braxton BerriosNYGWRInjured reserveFoot
Chauncey GolstonNYGDEInjured reserveNeck
Arden KeyINDDEInjured reserveHamstring
Jaxson DartNYGQBInjured reserveKnee
Brian BurnsNYGLBInjured reserveAnkle
Micheal ClemonsINDDEInjured reserveToe
Roy Robertson-HarrisNYGDTInjured reserve
Carson TowtINDTEInjured reserve
Sean McKeonINDTEQuestionable
DJ JamesNYGCBQuestionableUndisclosed
Korie BlackNYGCBIR, designated to returnUndisclosed
D.J. MontgomeryINDWRInjured reserveAbdomen
Calvin Austin IIINYGWRInjured reserveKnee
Cameron MitchellINDCBInjured reserve
Jarrick Bernard-ConverseNYGCBInjured reserve
Rico PaytonNYGCBInjured reserveUndisclosed
Gunner OlszewskiNYGWRInjured reserveAchilles
Thaddeus DixonNYGCBInjured reserve
Dante MillerNYGRBInjured Reserve
Rakeem Nunez-RochesNYGDTInjured Reserve
Chris BoardNYGLBInjured Reserve
TJ MooreNYGCBQuestionable
Wan'Dale RobinsonNYGWRInjured Reserve
Lucas PatrickNYGGQuestionable
C.J. RavenellNYGDEQuestionable
Beaux CollinsNYGWRQuestionable
Jalin HyattNYGWRQuestionable
Jack WilsonINDOTInjured Reserve
Braden SmithINDOTInjured Reserve
Coleman OwenINDWRInjured Reserve
Jacob PhillipsINDLBInjured Reserve
Chris LammonsINDCBInjured Reserve
Salvon AhmedINDRBInjured Reserve

NYG have taken 2 of the last 3 — 1 of the 3 landed inside a score.

Recent meetings
GameWinnerScoreVenue
2024 Week 17NYG45–33MetLife Stadium
2022 Week 17NYG38–10MetLife Stadium
2018 Week 16IND28–27Lucas Oil Stadium

Frequently asked questions

When do the Giants play the Colts?

New York Giants at Indianapolis Colts is Week 12 of the 2026 NFL season, kicking off on Sunday, November 29 at 1:00 PM ET at Lucas Oil Stadium.

What is the head-to-head record between the Giants and the Colts?

The recent series is NYG 2–1 over the last 3 meetings — the last one finished NYG 45–33 in 2024 (Week 17), and against the spread the series is NYG 3–0.

Who is injured for Giants vs Colts?

48 players carry a designation: 11 out and 16 questionable, including Cam Skattebo (NYG RB, Out), Jalen Travis (IND OT, Doubtful), Alec Pierce (IND WR, Injured reserve) and Cam Taylor-Britt (IND CB, Injured reserve).

Giants v Colts: teams and standings

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  • New York Giants Stats
  • Indianapolis Colts
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