Arizona Cardinals vs Kansas City Chiefs Prediction, Odds & Props — Week 11

The Arizona Cardinals visit the Kansas City Chiefs in Week 11 of the 2026 NFL season, on Sunday, November 22 at 1:00 PM ET at Arrowhead Stadium. Open air · Grass. The Cardinals are 3-6 (4th in the NFC West), the Chiefs 6-2 (2nd in the AFC West). The Cardinals went 2-4 down the stretch, the Chiefs 4-2.

In 2026 the Cardinals scored 19.8 points per game (26th in the NFL) and allowed 28.3 (31st in the NFL); the Chiefs scored 25.3 (10th in the NFL) and allowed 17.9 (3rd in the NFL).

Head-to-head, the recent series reads KC 2–0 over the last 2 meetings, at an average total of 52.5; against the spread it is KC 1–1, and the total has gone OVER 1–1. KC have won all 2 recent meetings.

Injury report: 22 players out and 23 questionable across the two teams — Michael Wilson (ARI WR, Injured reserve), Gardner Minshew II (ARI QB, Injured reserve), James Conner (ARI RB, IR, designated to return) and Kenny Yeboah (ARI TE, Out).

All Cardinals v Chiefs games

Arizona Cardinals vs Kansas City Chiefs: team comparison (2026 season, NFL rank in brackets)
Arizona CardinalsKansas City Chiefs
Record3-66-2
Division4th NFC W2nd AFC W
Last six resultsL L W L W LW W W L L W
Points / G19.8 (26th)25.3 (10th)
Total Yds / G333.8 (22nd)392.4 (4th)
Yards / Play4.9 (29th)6.4 (2nd)
Pass Yds / G231.1 (20th)254.6 (11th)
Rush Yds / G102.7 (22nd)137.8 (5th)
3rd Down %38% (15th)41.7% (9th)
1st Downs / G20.2 (15th)20.8 (9th)
Turnover Diff0 (17th)+4 (9th)
Pts Allowed / G28.3 (31st)17.9 (3rd)
Yds Allowed / G352.6 (19th)318 (7th)
Pass Yds Allowed230.7 (13th)220.5 (7th)
Rush Yds Allowed121.9 (19th)97.5 (10th)
Sacks19 (17th)14 (29th)
  • Arizona Cardinals stats, schedule and roster
  • Kansas City Chiefs stats, schedule and roster
Arizona Cardinals vs Kansas City Chiefs injury report
PlayerTeamPositionStatusInjury
Michael WilsonARIWRInjured reserveNot injury related - resting player
Gardner Minshew IIARIQBInjured reserveElbow
Jon Gaines IIARIGQuestionableAnkle
Mansoor DelaneKCCBQuestionableShoulder
Bam KnightARIRBQuestionableConcussion
Jayden WilliamsARIOTQuestionableKnee
Peter WoodsKCDTQuestionableNeck
Hjalte FroholdtARICQuestionableNot injury related - resting player
Jaylon MooreKCOTQuestionableConcussion
Xavier WorthyKCWRQuestionableShoulder
Patrick MahomesKCQBQuestionableKnee
Roy LopezARIDTQuestionableGroin
James ConnerARIRBIR, designated to returnFoot
Kenny YeboahARITEOutUndisclosed
Jeremiyah LoveARIRBInjured reserveAnkle
Kendrick BourneARIWRInjured reserveTibia
L'Jarius SneedKCCBInjured reserveKnee
Omarr Norman-LottKCDTReserve/PUPKnee
Jalen BrooksARIWRInjured reserveWrist
Tip ReimanARITEReserve/PUPAnkle
Brashard SmithKCRBInjured reserveHamstring
Josh SimmonsKCOTInjured reserveBack
Tyquan ThorntonKCWRInjured reserveAnkle
Paris Johnson Jr.ARIOTInjured reserveBiceps
Hunter LongARITEInjured reserveKnee
Will JohnsonARICBInjured reserveAnkle
Kaleb ProctorARIDTInjured reserve
Josh MinkinsARISQuestionable
Xavier WeaverARIWRQuestionableHamstring
Zachary CarterARIDTIR, designated to returnKnee
Jimmy HolidayKCWRInjured reserveUndisclosed
Jeff CaldwellKCWRInjured reserveKnee
Trey BensonARIRBInjured reserveKnee
Matt WaletzkoKCOTInjured reserveUndisclosed
Joey BlountARISInjured reserve
Chase BisontisARIGInjured reserve
Ethan DownsKCLBInjured reserveDowns
John Michael GyllenborgKCTEInjured reserve
Keaontay IngramKCRBInjured Reserve
Trent McDuffieKCCBInjured Reserve
Janarius RobinsonKCDEInjured Reserve
Brandon GeorgeKCLBQuestionable
Kader KohouKCCBQuestionable
Leo ChenalKCLBInjured Reserve
Deon BushKCSInjured Reserve
C.J. HansonKCGInjured Reserve
Chukwuebuka GodrickKCOTQuestionable
Chris OladokunKCQBInjured Reserve
Ethan DriskellKCOTOut
Cooper McDonaldKCLBInjured Reserve
Tyreke SmithKCDEOut
EJ SmithKCRBQuestionable
Jonah WilliamsARIOTInjured Reserve
Travis VokolekARITEInjured Reserve
Andre BaccelliaARIWRQuestionable
Jonah WilliamsARIDEQuestionable
Austin KeysARILBInjured Reserve
J.J. RussellARILBInjured Reserve
Jaden DavisARICBInjured Reserve
Bilal NicholsARIDTInjured Reserve
Channing TindallARILBQuestionable
Ihmir Smith-MarsetteARIWRQuestionable
Greg DortchARIWRInjured Reserve
Darren HallARISQuestionable
Jameson GeersARITEInjured Reserve
Marvin Harrison Jr.ARIWROut
Valentin SennARIOTQuestionable
Dadrion Taylor-DemersonARISQuestionable
Cameron RobertsonARILBOut
Garrett WilliamsARICBOut

KC have won all 2 recent meetings.

Recent meetings
GameWinnerScoreVenue
2022 Week 1KC44–21State Farm Stadium
2018 Week 10KC26–14GEHA Field at Arrowhead Stadium

Frequently asked questions

When do the Cardinals play the Chiefs?

Arizona Cardinals at Kansas City Chiefs is Week 11 of the 2026 NFL season, kicking off on Sunday, November 22 at 1:00 PM ET at Arrowhead Stadium.

What is the head-to-head record between the Cardinals and the Chiefs?

The recent series is KC 2–0 over the last 2 meetings — the last one finished KC 44–21 in 2022 (Week 1), and against the spread the series is KC 1–1.

Who is injured for Cardinals vs Chiefs?

70 players carry a designation: 22 out and 23 questionable, including Michael Wilson (ARI WR, Injured reserve), Gardner Minshew II (ARI QB, Injured reserve), James Conner (ARI RB, IR, designated to return) and Kenny Yeboah (ARI TE, Out).

Cardinals v Chiefs: teams and standings

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  • Arizona Cardinals Stats
  • Kansas City Chiefs
  • Kansas City Chiefs Stats
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  • NFC Standings
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