The Chargers lead 2-1 over the 3 games since 2019.
19 October 2025, in Week 7 of the 2025 season: the Colts won 38-24 at SoFi Stadium.
46.3 points a game: the Chargers average 24.7 and the Colts 21.7 in their 3 meetings since 2019.
The Chargers won by 17, 20-3, in Week 16 of 2022.