The Bills lead 4-2 over the 6 games since 2018.
20 October 2024, in Week 7 of the 2024 season: the Bills won 34-10 at Highmark Stadium.
43.5 points a game: the Bills average 24.8 and the Titans 18.7 in their 6 meetings since 2018.
The Bills won by 34, 41-7, in Week 2 of 2022.