The Texans lead 4-2 over the 6 games since 2018.
13 September 2026, in Week 1 of the 2026 season: the Bills won 36-31 at Reliant Stadium.
44.3 points a game: the Bills average 24.5 and the Texans 19.8 in their 6 meetings since 2018.
The Bills won by 40, 40-0, in Week 4 of 2021.