The Bills lead 3-1 over the 4 games since 2020.
12 October 2026, in Week 5 of the 2026 season: the Bills won 37-34 at SoFi Stadium.
66.3 points a game: the Bills average 36.3 and the Rams 30 in their 4 meetings since 2020.
The Bills won by 21, 31-10, in Week 1 of 2022.