Bills vs Lions: head to head

Frequently asked questions

Who leads the Bills vs Lions series?

The Bills lead 4-0 over the 4 games since 2018.

When did the Bills last play the Lions?

17 September 2026, in Week 2 of the 2026 season: the Bills won 41-31 at Highmark Stadium.

What is the average score when the Bills play the Lions?

60.5 points a game: the Bills average 32.8 and the Lions 27.8 in their 4 meetings since 2018.

What is the biggest win in the Bills vs Lions series?

The Bills won by 10, 41-31, in Week 2 of 2026.