Bills vs Chargers: head to head

Frequently asked questions

Who leads the Bills vs Chargers series?

The Bills lead 3-1 over the 4 games since 2018.

When did the Bills last play the Chargers?

27 September 2026, in Week 3 of the 2026 season: the Bills won 24-16 at Highmark Stadium.

What is the average score when the Bills play the Chargers?

45.3 points a game: the Bills average 23.8 and the Chargers 21.5 in their 4 meetings since 2018.

What is the biggest win in the Bills vs Chargers series?

The Chargers won by 11, 31-20, in Week 2 of 2018.