49ers vs Chargers: head to head

Frequently asked questions

Who leads the 49ers vs Chargers series?

The series is level at 1-1 over the 2 games since 2018.

When did the 49ers last play the Chargers?

13 November 2022, in Week 10 of the 2022 season: the 49ers won 22-16 at Levi's Stadium.

What is the average score when the 49ers play the Chargers?

47 points a game: the 49ers average 24.5 and the Chargers 22.5 in their 2 meetings since 2018.

What is the biggest win in the 49ers vs Chargers series?

The 49ers won by 6, 22-16, in Week 10 of 2022.

When do the 49ers play the Chargers next?

Thursday 17 December 2026, 8:15 PM ET, in Week 15: the 49ers at the Chargers, SoFi Stadium.