San Antonio Spurs vs Portland Trail Blazers Preview – April 21 2026

The San Antonio Spurs host the Portland Trail Blazers in San Antonio on Tuesday, April 21, tip-off 12:00 AM ET. Full game preview on Statz.

The Odds

Via Polymarket: SAS moneyline 1.17, POR 6.90. Spread: SAS -11.5. Total: Over 220.5. The biggest spread on the Tuesday card – San Antonio are overwhelming favorites on their home floor.

Team Form

Spurs hold a 3-1 series record over Portland this season, winning by an average of 8 points per game. They beat Portland 111-98 just two days prior on April 19, and 112-101 on April 8. Portland’s sole win came January 3 – a 115-110 Blazers victory. SAS win rate: 80%, POR: 60%.

SAS pace: 111 (fast). POR pace: 104.8 (fast). Both teams push tempo – the total is in play.

Injuries

San Antonio: De’Aaron Fox is out (ankle), along with Luke Kornet, Lindy Waters III, and Mason Plumlee. Fox at 16.2 PPG (last 10) is the key absence. Portland: Shaedon Sharpe is out, alongside long-term absentees Anfernee Simons (wrist), Zach Collins (toe), and Nick Richards (elbow).

Shooting Comparison

SAS: FG 46.6%, 3PT 36.6%, FT 76.3%. POR: FG 46.4%, 3PT 35.0%, FT 84.3%. Nearly identical field goal and three-point percentages but Portland win convincingly at the line. Offensive rating: SAS 123 vs POR 113.1 – San Antonio are the superior offensive team by a significant margin. Defensive rating: SAS 110.6 vs POR 107.5.

Key Players

For San Antonio without Fox: Victor Wembanyama carries the load at 32.7 PPG (last 10), Stephon Castle 18.1, Keldon Johnson 14.8, Dylan Harper 13.7. For Portland: Deni Avdija is the standout – carrying heavy minutes with massive prop output. Donovan Clingan at center.

Prop Streak Watch

Dylan Harper is on a 12-game OVER streak for Points + Rebounds (line 11.5, averaging 16.6) at 1.98 via FanDuel, and a 12-game OVER for Points (line 8.5, averaging 12.8) at 1.91. Keldon Johnson on a 12-game OVER for Points (line 9.5, averaging 15.6) at 1.88. Deni Avdija on a 7-game OVER streak for PRA (line 36.5, averaging 44.6) at 1.82 – he posted 60 PRA in the most recent game. Avdija’s Points + Assists line (29.5) also on a 7-game OVER with an average of 39.2.

Verdict

San Antonio’s offensive rating of 123 is among the best in the league. With Wembanyama leading in a fast-paced home game against a depleted Portland side missing Sharpe and Simons, the Spurs have the tools to cover a big number. The prop angle of the night is Avdija – a line of 36.5 PRA against a team giving up 110.6 on defense is workable. Harper’s lines remain modest relative to his output over the last three weeks.

Full game data: statz.ai/nba/games/san-antonio-spurs-vs-portland-trail-blazers-2026-04-21/preview

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