| Nico González | Newcastle United | @ Everton | 22% | 1.7 fouls a game; Booked in 8 of 31 games; Faces Harrison Armstrong (Central midfield), 1.4 fouls drawn a game; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Danilo Veiga | Lecce | @ Frosinone | 21% | Booked in 11 of 37 games |
| Víctor Valdepeñas | Fiorentina | v Atalanta | 20% | Booked in 2 of 9 games |
| Youssef Maleh | Lecce | @ Frosinone | 20% | Faces Giacomo Calò (Central midfield), 2.1 fouls drawn a game; Booked in 5 of 27 games |
| Gabriele Bracaglia | Frosinone | v Lecce | 20% | Booked in 13 of 28 games |
| Christ Inao Oulaï | Fiorentina | v Atalanta | 20% | Booked in 13 of 40 games; Faces Éderson (Central midfield), 1.4 fouls drawn a game |
| Harrison Armstrong | Everton | v Newcastle United | 18% | Booked in 4 of 27 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| James Tarkowski | Everton | v Newcastle United | 18% | Booked in 9 of 38 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Éderson | Atalanta | @ Fiorentina | 17% | Faces Christ Inao Oulaï (Central midfield), 1.7 fouls drawn a game; Fiorentina draw 14.5 fouls a game (average 11.9); Booked in 6 of 45 games |
| Franco Mastantuono | Fiorentina | v Atalanta | 17% | Booked in 4 of 26 games |
| Yoane Wissa | Newcastle United | @ Everton | 16% | Faces Harrison Armstrong (Central midfield), 1.4 fouls drawn a game; Booked in 6 of 32 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Tyler Dibling | Everton | v Newcastle United | 16% | Booked in 1 of 7 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Ilario Monterisi | Frosinone | v Lecce | 15% | 2.3 fouls a game; Booked in 4 of 24 games |
| Viery | Fiorentina | v Atalanta | 15% | Booked in 8 of 26 games; 1.6 fouls a game |
| Jake O'Brien | Everton | v Newcastle United | 15% | Booked in 6 of 38 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Mohamed Kaba | Lecce | @ Frosinone | 14% | Faces Giacomo Calò (Central midfield), 2.1 fouls drawn a game; Booked in 3 of 21 games |
| Thomas Kristensen | Atalanta | @ Fiorentina | 14% | Fiorentina draw 14.5 fouls a game (average 11.9); Booked in 5 of 30 games |
| Malick Thiaw | Newcastle United | @ Everton | 14% | Booked in 10 of 56 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Romano Schmid | Frosinone | v Lecce | 13% | Faces Mohamed Kaba (Central midfield), 2.1 fouls drawn a game; Booked in 7 of 47 games |
| Oumar Ngom | Lecce | @ Frosinone | 13% | Faces Giacomo Calò (Central midfield), 2.1 fouls drawn a game; Booked in 4 of 33 games |
| Álex Jiménez | Fiorentina | v Atalanta | 13% | Faces Jonathan Rowe (Left midfield), 1.9 fouls drawn a game; Booked in 8 of 33 games |
| Jacob Murphy | Newcastle United | @ Everton | 13% | Booked in 4 of 34 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Ainsley Maitland-Niles | Everton | v Newcastle United | 13% | Booked in 7 of 34 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Sven Botman | Newcastle United | @ Everton | 13% | Booked in 4 of 34 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Jamil Siebert | Lecce | @ Frosinone | 13% | Booked in 4 of 25 games |
| Giorgi Kvernadze | Frosinone | v Lecce | 13% | Faces Danilo Veiga (Right-back), 1.4 fouls drawn a game; Booked in 6 of 41 games |
| Nikola Krstović | Atalanta | @ Fiorentina | 13% | Fiorentina draw 14.5 fouls a game (average 11.9); 1.6 fouls a game; Booked in 5 of 47 games |
| Alieu Njie | Fiorentina | v Atalanta | 13% | Booked in 2 of 16 games |
| Hayden Hackney | Everton | v Newcastle United | 13% | 1.5 fouls a game; Booked in 1 of 31 games; Lenient referee: Farai Hallam, 3.4 yellows a game |
| Lewis Hall | Newcastle United | @ Everton | 13% | Booked in 6 of 54 games; Lenient referee: Farai Hallam, 3.4 yellows a game |