| 13/08/2021 | 21:00 | Brentford vs Arsenal | 2-0 |
| 14/08/2021 | 13:30 | Manchester United vs Leeds United | 5-1 |
| 14/08/2021 | 16:00 | Burnley vs Brighton & Hove Albion | 1-2 |
| 14/08/2021 | 16:00 | Chelsea vs Crystal Palace | 3-0 |
| 14/08/2021 | 16:00 | Everton vs Southampton | 3-1 |
| 14/08/2021 | 16:00 | Leicester City vs Wolverhampton Wanderers | 1-0 |
| 14/08/2021 | 16:00 | Watford vs Aston Villa | 3-2 |
| 14/08/2021 | 18:30 | Norwich City vs Liverpool | 0-3 |
| 15/08/2021 | 15:00 | Newcastle United vs West Ham United | 2-4 |
| 15/08/2021 | 17:30 | Tottenham Hotspur vs Manchester City | 1-0 |
| 21/08/2021 | 13:30 | Liverpool vs Burnley | 2-0 |
| 21/08/2021 | 16:00 | Aston Villa vs Newcastle United | 2-0 |
| 21/08/2021 | 16:00 | Crystal Palace vs Brentford | 0-0 |
| 21/08/2021 | 16:00 | Leeds United vs Everton | 2-2 |
| 21/08/2021 | 16:00 | Manchester City vs Norwich City | 5-0 |
| 21/08/2021 | 18:30 | Brighton & Hove Albion vs Watford | 2-0 |
| 22/08/2021 | 15:00 | Southampton vs Manchester United | 1-1 |
| 22/08/2021 | 15:00 | Wolverhampton Wanderers vs Tottenham Hotspur | 0-1 |
| 22/08/2021 | 17:30 | Arsenal vs Chelsea | 0-2 |
| 23/08/2021 | 21:00 | West Ham United vs Leicester City | 4-1 |
| 28/08/2021 | 13:30 | Manchester City vs Arsenal | 5-0 |
| 28/08/2021 | 16:00 | Aston Villa vs Brentford | 1-1 |
| 28/08/2021 | 16:00 | Brighton & Hove Albion vs Everton | 0-2 |
| 28/08/2021 | 16:00 | Newcastle United vs Southampton | 2-2 |
| 28/08/2021 | 16:00 | Norwich City vs Leicester City | 1-2 |
| 28/08/2021 | 16:00 | West Ham United vs Crystal Palace | 2-2 |
| 28/08/2021 | 18:30 | Liverpool vs Chelsea | 1-1 |
| 29/08/2021 | 15:00 | Burnley vs Leeds United | 1-1 |
| 29/08/2021 | 15:00 | Tottenham Hotspur vs Watford | 1-0 |
| 29/08/2021 | 17:30 | Wolverhampton Wanderers vs Manchester United | 0-1 |
| 11/09/2021 | 13:30 | Crystal Palace vs Tottenham Hotspur | 3-0 |
| 11/09/2021 | 16:00 | Arsenal vs Norwich City | 1-0 |
| 11/09/2021 | 16:00 | Brentford vs Brighton & Hove Albion | 0-1 |
| 11/09/2021 | 16:00 | Leicester City vs Manchester City | 0-1 |
| 11/09/2021 | 16:00 | Manchester United vs Newcastle United | 4-1 |
| 11/09/2021 | 16:00 | Southampton vs West Ham United | 0-0 |
| 11/09/2021 | 16:00 | Watford vs Wolverhampton Wanderers | 0-2 |
| 11/09/2021 | 18:30 | Chelsea vs Aston Villa | 3-0 |
| 12/09/2021 | 17:30 | Leeds United vs Liverpool | 0-3 |
| 13/09/2021 | 21:00 | Everton vs Burnley | 3-1 |
| 17/09/2021 | 21:00 | Newcastle United vs Leeds United | 1-1 |
| 18/09/2021 | 13:30 | Wolverhampton Wanderers vs Brentford | 0-2 |
| 18/09/2021 | 16:00 | Burnley vs Arsenal | 0-1 |
| 18/09/2021 | 16:00 | Liverpool vs Crystal Palace | 3-0 |
| 18/09/2021 | 16:00 | Manchester City vs Southampton | 0-0 |
| 18/09/2021 | 16:00 | Norwich City vs Watford | 1-3 |
| 18/09/2021 | 18:30 | Aston Villa vs Everton | 3-0 |
| 19/09/2021 | 15:00 | Brighton & Hove Albion vs Leicester City | 2-1 |
| 19/09/2021 | 15:00 | West Ham United vs Manchester United | 1-2 |
| 19/09/2021 | 17:30 | Tottenham Hotspur vs Chelsea | 0-3 |
| 25/09/2021 | 13:30 | Chelsea vs Manchester City | 0-1 |
| 25/09/2021 | 13:30 | Manchester United vs Aston Villa | 0-1 |
| 25/09/2021 | 16:00 | Everton vs Norwich City | 2-0 |
| 25/09/2021 | 16:00 | Leeds United vs West Ham United | 1-2 |
| 25/09/2021 | 16:00 | Leicester City vs Burnley | 2-2 |
| 25/09/2021 | 16:00 | Watford vs Newcastle United | 1-1 |
| 25/09/2021 | 18:30 | Brentford vs Liverpool | 3-3 |
| 26/09/2021 | 15:00 | Southampton vs Wolverhampton Wanderers | 0-1 |
| 26/09/2021 | 17:30 | Arsenal vs Tottenham Hotspur | 3-1 |
| 27/09/2021 | 21:00 | Crystal Palace vs Brighton & Hove Albion | 1-1 |
| 02/10/2021 | 13:30 | Manchester United vs Everton | 1-1 |
| 02/10/2021 | 16:00 | Burnley vs Norwich City | 0-0 |
| 02/10/2021 | 16:00 | Chelsea vs Southampton | 3-1 |
| 02/10/2021 | 16:00 | Leeds United vs Watford | 1-0 |
| 02/10/2021 | 16:00 | Wolverhampton Wanderers vs Newcastle United | 2-1 |
| 02/10/2021 | 18:30 | Brighton & Hove Albion vs Arsenal | 0-0 |
| 03/10/2021 | 15:00 | Crystal Palace vs Leicester City | 2-2 |
| 03/10/2021 | 15:00 | Tottenham Hotspur vs Aston Villa | 2-1 |
| 03/10/2021 | 15:00 | West Ham United vs Brentford | 1-2 |
| 03/10/2021 | 17:30 | Liverpool vs Manchester City | 2-2 |
| 16/10/2021 | 13:30 | Watford vs Liverpool | 0-5 |
| 16/10/2021 | 16:00 | Aston Villa vs Wolverhampton Wanderers | 2-3 |
| 16/10/2021 | 16:00 | Leicester City vs Manchester United | 4-2 |
| 16/10/2021 | 16:00 | Manchester City vs Burnley | 2-0 |
| 16/10/2021 | 16:00 | Norwich City vs Brighton & Hove Albion | 0-0 |
| 16/10/2021 | 16:00 | Southampton vs Leeds United | 1-0 |
| 16/10/2021 | 18:30 | Brentford vs Chelsea | 0-1 |
| 17/10/2021 | 15:00 | Everton vs West Ham United | 0-1 |
| 17/10/2021 | 17:30 | Newcastle United vs Tottenham Hotspur | 2-3 |
| 18/10/2021 | 21:00 | Arsenal vs Crystal Palace | 2-2 |
| 22/10/2021 | 21:00 | Arsenal vs Aston Villa | 3-1 |
| 23/10/2021 | 13:30 | Chelsea vs Norwich City | 7-0 |
| 23/10/2021 | 16:00 | Crystal Palace vs Newcastle United | 1-1 |
| 23/10/2021 | 16:00 | Everton vs Watford | 2-5 |
| 23/10/2021 | 16:00 | Leeds United vs Wolverhampton Wanderers | 1-1 |
| 23/10/2021 | 16:00 | Southampton vs Burnley | 2-2 |
| 23/10/2021 | 18:30 | Brighton & Hove Albion vs Manchester City | 1-4 |
| 24/10/2021 | 15:00 | Brentford vs Leicester City | 1-2 |
| 24/10/2021 | 15:00 | West Ham United vs Tottenham Hotspur | 1-0 |
| 24/10/2021 | 17:30 | Manchester United vs Liverpool | 0-5 |
| 30/10/2021 | 13:30 | Leicester City vs Arsenal | 0-2 |
| 30/10/2021 | 16:00 | Burnley vs Brentford | 3-1 |
| 30/10/2021 | 16:00 | Liverpool vs Brighton & Hove Albion | 2-2 |
| 30/10/2021 | 16:00 | Manchester City vs Crystal Palace | 0-2 |
| 30/10/2021 | 16:00 | Newcastle United vs Chelsea | 0-3 |
| 30/10/2021 | 16:00 | Watford vs Southampton | 0-1 |
| 30/10/2021 | 18:30 | Tottenham Hotspur vs Manchester United | 0-3 |
| 31/10/2021 | 15:00 | Norwich City vs Leeds United | 1-2 |
| 31/10/2021 | 17:30 | Aston Villa vs West Ham United | 1-4 |
| 01/11/2021 | 21:00 | Wolverhampton Wanderers vs Everton | 2-1 |
| 05/11/2021 | 21:00 | Southampton vs Aston Villa | 1-0 |
| 06/11/2021 | 13:30 | Manchester United vs Manchester City | 0-2 |
| 06/11/2021 | 16:00 | Brentford vs Norwich City | 1-2 |
| 06/11/2021 | 16:00 | Chelsea vs Burnley | 1-1 |
| 06/11/2021 | 16:00 | Crystal Palace vs Wolverhampton Wanderers | 2-0 |
| 06/11/2021 | 18:30 | Brighton & Hove Albion vs Newcastle United | 1-1 |
| 07/11/2021 | 15:00 | Arsenal vs Watford | 1-0 |
| 07/11/2021 | 15:00 | Everton vs Tottenham Hotspur | 0-0 |
| 07/11/2021 | 15:00 | Leeds United vs Leicester City | 1-1 |
| 07/11/2021 | 17:30 | West Ham United vs Liverpool | 3-2 |
| 20/11/2021 | 13:30 | Leicester City vs Chelsea | 0-3 |
| 20/11/2021 | 16:00 | Aston Villa vs Brighton & Hove Albion | 2-0 |
| 20/11/2021 | 16:00 | Burnley vs Crystal Palace | 3-3 |
| 20/11/2021 | 16:00 | Newcastle United vs Brentford | 3-3 |
| 20/11/2021 | 16:00 | Norwich City vs Southampton | 2-1 |
| 20/11/2021 | 16:00 | Watford vs Manchester United | 4-1 |
| 20/11/2021 | 16:00 | Wolverhampton Wanderers vs West Ham United | 1-0 |
| 20/11/2021 | 18:30 | Liverpool vs Arsenal | 4-0 |
| 21/11/2021 | 15:00 | Manchester City vs Everton | 3-0 |
| 21/11/2021 | 17:30 | Tottenham Hotspur vs Leeds United | 2-1 |
| 27/11/2021 | 13:30 | Arsenal vs Newcastle United | 2-0 |
| 27/11/2021 | 16:00 | Crystal Palace vs Aston Villa | 1-2 |
| 27/11/2021 | 16:00 | Liverpool vs Southampton | 4-0 |
| 27/11/2021 | 16:00 | Norwich City vs Wolverhampton Wanderers | 0-0 |
| 27/11/2021 | 18:30 | Brighton & Hove Albion vs Leeds United | 0-0 |
| 28/11/2021 | 15:00 | Brentford vs Everton | 1-0 |
| 28/11/2021 | 15:00 | Leicester City vs Watford | 4-2 |
| 28/11/2021 | 15:00 | Manchester City vs West Ham United | 2-1 |
| 28/11/2021 | 17:30 | Chelsea vs Manchester United | 1-1 |
| 23/02/2022 | 20:30 | Burnley vs Tottenham Hotspur | 1-0 |
| 30/11/2021 | 20:30 | Newcastle United vs Norwich City | 1-1 |
| 30/11/2021 | 21:15 | Leeds United vs Crystal Palace | 1-0 |
| 01/12/2021 | 20:30 | Watford vs Chelsea | 1-2 |
| 01/12/2021 | 20:30 | West Ham United vs Brighton & Hove Albion | 1-1 |
| 01/12/2021 | 20:30 | Wolverhampton Wanderers vs Burnley | 0-0 |
| 01/12/2021 | 20:30 | Southampton vs Leicester City | 2-2 |
| 01/12/2021 | 21:15 | Aston Villa vs Manchester City | 1-2 |
| 01/12/2021 | 21:15 | Everton vs Liverpool | 1-4 |
| 02/12/2021 | 20:30 | Tottenham Hotspur vs Brentford | 2-0 |
| 02/12/2021 | 21:15 | Manchester United vs Arsenal | 3-2 |
| 04/12/2021 | 13:30 | West Ham United vs Chelsea | 3-2 |
| 04/12/2021 | 16:00 | Newcastle United vs Burnley | 1-0 |
| 04/12/2021 | 16:00 | Southampton vs Brighton & Hove Albion | 1-1 |
| 04/12/2021 | 16:00 | Wolverhampton Wanderers vs Liverpool | 0-1 |
| 04/12/2021 | 18:30 | Watford vs Manchester City | 1-3 |
| 05/12/2021 | 15:00 | Leeds United vs Brentford | 2-2 |
| 05/12/2021 | 15:00 | Manchester United vs Crystal Palace | 1-0 |
| 05/12/2021 | 15:00 | Tottenham Hotspur vs Norwich City | 3-0 |
| 05/12/2021 | 17:30 | Aston Villa vs Leicester City | 2-1 |
| 06/12/2021 | 21:00 | Everton vs Arsenal | 2-1 |
| 10/12/2021 | 21:00 | Brentford vs Watford | 2-1 |
| 11/12/2021 | 13:30 | Manchester City vs Wolverhampton Wanderers | 1-0 |
| 11/12/2021 | 16:00 | Arsenal vs Southampton | 3-0 |
| 11/12/2021 | 16:00 | Chelsea vs Leeds United | 3-2 |
| 11/12/2021 | 16:00 | Liverpool vs Aston Villa | 1-0 |
| 11/12/2021 | 18:30 | Norwich City vs Manchester United | 0-1 |
| 12/12/2021 | 15:00 | Burnley vs West Ham United | 0-0 |
| 12/12/2021 | 15:00 | Leicester City vs Newcastle United | 4-0 |
| 12/12/2021 | 17:30 | Crystal Palace vs Everton | 3-1 |
| 16/03/2022 | 20:30 | Brighton & Hove Albion vs Tottenham Hotspur | 0-2 |
| 14/12/2021 | 20:45 | Norwich City vs Aston Villa | 0-2 |
| 14/12/2021 | 21:00 | Manchester City vs Leeds United | 7-0 |
| 15/12/2021 | 20:30 | Brighton & Hove Albion vs Wolverhampton Wanderers | 0-1 |
| 15/12/2021 | 20:30 | Crystal Palace vs Southampton | 2-2 |
| 15/12/2021 | 21:00 | Arsenal vs West Ham United | 2-0 |
| 16/12/2021 | 20:45 | Chelsea vs Everton | 1-1 |
| 16/12/2021 | 21:00 | Liverpool vs Newcastle United | 3-1 |
| 19/01/2022 | 20:30 | Leicester City vs Tottenham Hotspur | 2-3 |
| 19/01/2022 | 21:00 | Brentford vs Manchester United | 1-3 |
| 05/02/2022 | 19:00 | Burnley vs Watford | 0-0 |
| 18/12/2021 | 18:30 | Leeds United vs Arsenal | 1-4 |
| 19/12/2021 | 15:00 | Newcastle United vs Manchester City | 0-4 |
| 19/12/2021 | 15:00 | Wolverhampton Wanderers vs Chelsea | 0-0 |
| 19/12/2021 | 17:30 | Tottenham Hotspur vs Liverpool | 2-2 |
| 11/01/2022 | 20:45 | Southampton vs Brentford | 4-1 |
| 12/01/2022 | 20:45 | West Ham United vs Norwich City | 2-0 |
| 15/02/2022 | 21:15 | Manchester United vs Brighton & Hove Albion | 2-0 |
| 23/02/2022 | 20:30 | Watford vs Crystal Palace | 1-4 |
| 20/04/2022 | 20:45 | Everton vs Leicester City | 1-1 |
| 19/05/2022 | 21:00 | Aston Villa vs Burnley | 1-1 |
| 26/12/2021 | 16:00 | Manchester City vs Leicester City | 6-3 |
| 26/12/2021 | 16:00 | Norwich City vs Arsenal | 0-5 |
| 26/12/2021 | 16:00 | Tottenham Hotspur vs Crystal Palace | 3-0 |
| 26/12/2021 | 16:00 | West Ham United vs Southampton | 2-3 |
| 26/12/2021 | 18:30 | Aston Villa vs Chelsea | 1-3 |
| 26/12/2021 | 21:00 | Brighton & Hove Albion vs Brentford | 2-0 |
| 27/12/2021 | 21:00 | Newcastle United vs Manchester United | 1-1 |
| 23/02/2022 | 20:45 | Liverpool vs Leeds United | 6-0 |
| 10/03/2022 | 20:30 | Wolverhampton Wanderers vs Watford | 4-0 |
| 06/04/2022 | 20:30 | Burnley vs Everton | 3-2 |
| 28/12/2021 | 16:00 | Crystal Palace vs Norwich City | 3-0 |
| 28/12/2021 | 16:00 | Southampton vs Tottenham Hotspur | 1-1 |
| 28/12/2021 | 16:00 | Watford vs West Ham United | 1-4 |
| 28/12/2021 | 21:00 | Leicester City vs Liverpool | 1-0 |
| 29/12/2021 | 20:30 | Chelsea vs Brighton & Hove Albion | 1-1 |
| 29/12/2021 | 21:15 | Brentford vs Manchester City | 0-1 |
| 30/12/2021 | 21:15 | Manchester United vs Burnley | 3-1 |
| 24/02/2022 | 20:45 | Arsenal vs Wolverhampton Wanderers | 2-1 |
| 10/03/2022 | 20:45 | Leeds United vs Aston Villa | 0-3 |
| 17/03/2022 | 20:45 | Everton vs Newcastle United | 1-0 |
| 01/01/2022 | 13:30 | Arsenal vs Manchester City | 1-2 |
| 01/01/2022 | 16:00 | Watford vs Tottenham Hotspur | 0-1 |
| 01/01/2022 | 18:30 | Crystal Palace vs West Ham United | 2-3 |
| 02/01/2022 | 15:00 | Brentford vs Aston Villa | 2-1 |
| 02/01/2022 | 15:00 | Everton vs Brighton & Hove Albion | 2-3 |
| 02/01/2022 | 15:00 | Leeds United vs Burnley | 3-1 |
| 02/01/2022 | 17:30 | Chelsea vs Liverpool | 2-2 |
| 03/01/2022 | 18:30 | Manchester United vs Wolverhampton Wanderers | 0-1 |
| 10/03/2022 | 20:30 | Southampton vs Newcastle United | 1-2 |
| 11/05/2022 | 20:45 | Leicester City vs Norwich City | 3-0 |
| 14/01/2022 | 21:00 | Brighton & Hove Albion vs Crystal Palace | 1-1 |
| 15/01/2022 | 13:30 | Manchester City vs Chelsea | 1-0 |
| 15/01/2022 | 16:00 | Newcastle United vs Watford | 1-1 |
| 15/01/2022 | 16:00 | Norwich City vs Everton | 2-1 |
| 15/01/2022 | 16:00 | Wolverhampton Wanderers vs Southampton | 3-1 |
| 15/01/2022 | 18:30 | Aston Villa vs Manchester United | 2-2 |
| 16/01/2022 | 15:00 | Liverpool vs Brentford | 3-0 |
| 16/01/2022 | 15:00 | West Ham United vs Leeds United | 2-3 |
| 01/03/2022 | 20:45 | Burnley vs Leicester City | 0-2 |
| 12/05/2022 | 20:45 | Tottenham Hotspur vs Arsenal | 3-0 |
| 18/01/2022 | 21:00 | Brighton & Hove Albion vs Chelsea | 1-1 |
| 08/02/2022 | 20:45 | West Ham United vs Watford | 1-0 |
| 08/02/2022 | 20:45 | Newcastle United vs Everton | 3-1 |
| 08/02/2022 | 21:00 | Burnley vs Manchester United | 1-1 |
| 09/02/2022 | 20:45 | Norwich City vs Crystal Palace | 1-1 |
| 09/02/2022 | 20:45 | Tottenham Hotspur vs Southampton | 2-3 |
| 09/02/2022 | 20:45 | Manchester City vs Brentford | 2-0 |
| 09/02/2022 | 21:00 | Aston Villa vs Leeds United | 3-3 |
| 10/02/2022 | 20:45 | Wolverhampton Wanderers vs Arsenal | 0-1 |
| 10/02/2022 | 20:45 | Liverpool vs Leicester City | 2-0 |
| 21/01/2022 | 21:00 | Watford vs Norwich City | 0-3 |
| 22/01/2022 | 13:30 | Everton vs Aston Villa | 0-1 |
| 22/01/2022 | 16:00 | Brentford vs Wolverhampton Wanderers | 1-2 |
| 22/01/2022 | 16:00 | Leeds United vs Newcastle United | 0-1 |
| 22/01/2022 | 16:00 | Manchester United vs West Ham United | 1-0 |
| 22/01/2022 | 18:30 | Southampton vs Manchester City | 1-1 |
| 23/01/2022 | 15:00 | Arsenal vs Burnley | 0-0 |
| 23/01/2022 | 15:00 | Crystal Palace vs Liverpool | 1-3 |
| 23/01/2022 | 15:00 | Leicester City vs Brighton & Hove Albion | 1-1 |
| 23/01/2022 | 17:30 | Chelsea vs Tottenham Hotspur | 2-0 |
| 12/02/2022 | 13:30 | Manchester United vs Southampton | 1-1 |
| 12/02/2022 | 16:00 | Brentford vs Crystal Palace | 0-0 |
| 12/02/2022 | 16:00 | Everton vs Leeds United | 3-0 |
| 12/02/2022 | 16:00 | Watford vs Brighton & Hove Albion | 0-2 |
| 12/02/2022 | 18:30 | Norwich City vs Manchester City | 0-4 |
| 13/02/2022 | 15:00 | Burnley vs Liverpool | 0-1 |
| 13/02/2022 | 15:00 | Newcastle United vs Aston Villa | 1-0 |
| 13/02/2022 | 15:00 | Tottenham Hotspur vs Wolverhampton Wanderers | 0-2 |
| 13/02/2022 | 17:30 | Leicester City vs West Ham United | 2-2 |
| 20/04/2022 | 20:45 | Chelsea vs Arsenal | 2-4 |
| 19/02/2022 | 13:30 | West Ham United vs Newcastle United | 1-1 |
| 19/02/2022 | 16:00 | Arsenal vs Brentford | 2-1 |
| 19/02/2022 | 16:00 | Aston Villa vs Watford | 0-1 |
| 19/02/2022 | 16:00 | Brighton & Hove Albion vs Burnley | 0-3 |
| 19/02/2022 | 16:00 | Crystal Palace vs Chelsea | 0-1 |
| 19/02/2022 | 16:00 | Liverpool vs Norwich City | 3-1 |
| 19/02/2022 | 16:00 | Southampton vs Everton | 2-0 |
| 19/02/2022 | 18:30 | Manchester City vs Tottenham Hotspur | 2-3 |
| 20/02/2022 | 15:00 | Leeds United vs Manchester United | 2-4 |
| 20/02/2022 | 17:30 | Wolverhampton Wanderers vs Leicester City | 2-1 |
| 25/02/2022 | 21:00 | Southampton vs Norwich City | 2-0 |
| 26/02/2022 | 13:30 | Leeds United vs Tottenham Hotspur | 0-4 |
| 26/02/2022 | 16:00 | Brentford vs Newcastle United | 0-2 |
| 26/02/2022 | 16:00 | Crystal Palace vs Burnley | 1-1 |
| 26/02/2022 | 16:00 | Manchester United vs Watford | 0-0 |
| 26/02/2022 | 16:30 | Brighton & Hove Albion vs Aston Villa | 0-2 |
| 26/02/2022 | 18:30 | Everton vs Manchester City | 0-1 |
| 27/02/2022 | 15:00 | West Ham United vs Wolverhampton Wanderers | 1-0 |
| 16/03/2022 | 21:15 | Arsenal vs Liverpool | 0-2 |
| 19/05/2022 | 21:00 | Chelsea vs Leicester City | 1-1 |
| 05/03/2022 | 13:30 | Leicester City vs Leeds United | 1-0 |
| 05/03/2022 | 16:00 | Aston Villa vs Southampton | 4-0 |
| 05/03/2022 | 16:00 | Burnley vs Chelsea | 0-4 |
| 05/03/2022 | 16:00 | Newcastle United vs Brighton & Hove Albion | 2-1 |
| 05/03/2022 | 16:00 | Norwich City vs Brentford | 1-3 |
| 05/03/2022 | 16:00 | Wolverhampton Wanderers vs Crystal Palace | 0-2 |
| 05/03/2022 | 18:30 | Liverpool vs West Ham United | 1-0 |
| 06/03/2022 | 15:00 | Watford vs Arsenal | 2-3 |
| 06/03/2022 | 17:30 | Manchester City vs Manchester United | 4-1 |
| 07/03/2022 | 21:00 | Tottenham Hotspur vs Everton | 5-0 |
| 10/03/2022 | 20:30 | Norwich City vs Chelsea | 1-3 |
| 18/03/2022 | 21:00 | Wolverhampton Wanderers vs Leeds United | 2-3 |
| 19/03/2022 | 13:30 | Aston Villa vs Arsenal | 0-1 |
| 20/03/2022 | 15:00 | Leicester City vs Brentford | 2-1 |
| 20/03/2022 | 17:30 | Tottenham Hotspur vs West Ham United | 3-1 |
| 19/04/2022 | 21:00 | Liverpool vs Manchester United | 4-0 |
| 20/04/2022 | 20:45 | Newcastle United vs Crystal Palace | 1-0 |
| 20/04/2022 | 21:00 | Manchester City vs Brighton & Hove Albion | 3-0 |
| 21/04/2022 | 20:45 | Burnley vs Southampton | 2-0 |
| 11/05/2022 | 20:45 | Watford vs Everton | 0-0 |
| 12/03/2022 | 13:30 | Brighton & Hove Albion vs Liverpool | 0-2 |
| 12/03/2022 | 16:00 | Brentford vs Burnley | 2-0 |
| 12/03/2022 | 18:30 | Manchester United vs Tottenham Hotspur | 3-2 |
| 13/03/2022 | 15:00 | Chelsea vs Newcastle United | 1-0 |
| 13/03/2022 | 15:00 | Everton vs Wolverhampton Wanderers | 0-1 |
| 13/03/2022 | 15:00 | Leeds United vs Norwich City | 2-1 |
| 13/03/2022 | 15:00 | Southampton vs Watford | 1-2 |
| 13/03/2022 | 15:00 | West Ham United vs Aston Villa | 2-1 |
| 13/03/2022 | 17:30 | Arsenal vs Leicester City | 2-0 |
| 14/03/2022 | 21:00 | Crystal Palace vs Manchester City | 0-0 |
| 02/04/2022 | 13:30 | Liverpool vs Watford | 2-0 |
| 02/04/2022 | 16:00 | Brighton & Hove Albion vs Norwich City | 0-0 |
| 02/04/2022 | 16:00 | Burnley vs Manchester City | 0-2 |
| 02/04/2022 | 16:00 | Chelsea vs Brentford | 1-4 |
| 02/04/2022 | 16:00 | Leeds United vs Southampton | 1-1 |
| 02/04/2022 | 16:00 | Wolverhampton Wanderers vs Aston Villa | 2-1 |
| 02/04/2022 | 18:30 | Manchester United vs Leicester City | 1-1 |
| 03/04/2022 | 15:00 | West Ham United vs Everton | 2-1 |
| 03/04/2022 | 17:30 | Tottenham Hotspur vs Newcastle United | 5-1 |
| 04/04/2022 | 21:00 | Crystal Palace vs Arsenal | 3-0 |
| 08/04/2022 | 21:00 | Newcastle United vs Wolverhampton Wanderers | 1-0 |
| 09/04/2022 | 13:30 | Everton vs Manchester United | 1-0 |
| 09/04/2022 | 16:00 | Arsenal vs Brighton & Hove Albion | 1-2 |
| 09/04/2022 | 16:00 | Southampton vs Chelsea | 0-6 |
| 09/04/2022 | 16:00 | Watford vs Leeds United | 0-3 |
| 09/04/2022 | 18:30 | Aston Villa vs Tottenham Hotspur | 0-4 |
| 10/04/2022 | 15:00 | Brentford vs West Ham United | 2-0 |
| 10/04/2022 | 15:00 | Leicester City vs Crystal Palace | 2-1 |
| 10/04/2022 | 15:00 | Norwich City vs Burnley | 2-0 |
| 10/04/2022 | 17:30 | Manchester City vs Liverpool | 2-2 |
| 16/04/2022 | 13:30 | Tottenham Hotspur vs Brighton & Hove Albion | 0-1 |
| 16/04/2022 | 16:00 | Manchester United vs Norwich City | 3-2 |
| 16/04/2022 | 16:00 | Southampton vs Arsenal | 1-0 |
| 16/04/2022 | 16:00 | Watford vs Brentford | 1-2 |
| 17/04/2022 | 15:15 | Newcastle United vs Leicester City | 2-1 |
| 17/04/2022 | 15:15 | West Ham United vs Burnley | 1-1 |
| 10/05/2022 | 21:00 | Aston Villa vs Liverpool | 1-2 |
| 11/05/2022 | 20:30 | Leeds United vs Chelsea | 0-3 |
| 11/05/2022 | 21:15 | Wolverhampton Wanderers vs Manchester City | 1-5 |
| 19/05/2022 | 20:45 | Everton vs Crystal Palace | 3-2 |
| 23/04/2022 | 13:30 | Arsenal vs Manchester United | 3-1 |
| 23/04/2022 | 16:00 | Leicester City vs Aston Villa | 0-0 |
| 23/04/2022 | 16:00 | Manchester City vs Watford | 5-1 |
| 23/04/2022 | 16:00 | Norwich City vs Newcastle United | 0-3 |
| 23/04/2022 | 18:30 | Brentford vs Tottenham Hotspur | 0-0 |
| 24/04/2022 | 15:00 | Brighton & Hove Albion vs Southampton | 2-2 |
| 24/04/2022 | 15:00 | Burnley vs Wolverhampton Wanderers | 1-0 |
| 24/04/2022 | 15:00 | Chelsea vs West Ham United | 1-0 |
| 24/04/2022 | 17:30 | Liverpool vs Everton | 2-0 |
| 25/04/2022 | 21:00 | Crystal Palace vs Leeds United | 0-0 |
| 28/04/2022 | 20:45 | Manchester United vs Chelsea | 1-1 |
| 15/05/2022 | 13:00 | Tottenham Hotspur vs Burnley | 1-0 |
| 15/05/2022 | 15:00 | Aston Villa vs Crystal Palace | 1-1 |
| 15/05/2022 | 15:00 | Leeds United vs Brighton & Hove Albion | 1-1 |
| 15/05/2022 | 15:00 | Watford vs Leicester City | 1-5 |
| 15/05/2022 | 15:00 | West Ham United vs Manchester City | 2-2 |
| 15/05/2022 | 15:00 | Wolverhampton Wanderers vs Norwich City | 1-1 |
| 15/05/2022 | 17:30 | Everton vs Brentford | 2-3 |
| 16/05/2022 | 21:00 | Newcastle United vs Arsenal | 2-0 |
| 17/05/2022 | 20:45 | Southampton vs Liverpool | 1-2 |
| 30/04/2022 | 13:30 | Newcastle United vs Liverpool | 0-1 |
| 30/04/2022 | 16:00 | Aston Villa vs Norwich City | 2-0 |
| 30/04/2022 | 16:00 | Southampton vs Crystal Palace | 1-2 |
| 30/04/2022 | 16:00 | Watford vs Burnley | 1-2 |
| 30/04/2022 | 16:00 | Wolverhampton Wanderers vs Brighton & Hove Albion | 0-3 |
| 30/04/2022 | 18:30 | Leeds United vs Manchester City | 0-4 |
| 01/05/2022 | 15:00 | Everton vs Chelsea | 1-0 |
| 01/05/2022 | 15:00 | Tottenham Hotspur vs Leicester City | 3-1 |
| 01/05/2022 | 17:30 | West Ham United vs Arsenal | 1-2 |
| 02/05/2022 | 21:00 | Manchester United vs Brentford | 3-0 |
| 07/05/2022 | 16:00 | Brentford vs Southampton | 3-0 |
| 07/05/2022 | 16:00 | Burnley vs Aston Villa | 1-3 |
| 07/05/2022 | 16:00 | Chelsea vs Wolverhampton Wanderers | 2-2 |
| 07/05/2022 | 16:00 | Crystal Palace vs Watford | 1-0 |
| 07/05/2022 | 18:30 | Brighton & Hove Albion vs Manchester United | 4-0 |
| 07/05/2022 | 20:45 | Liverpool vs Tottenham Hotspur | 1-1 |
| 08/05/2022 | 15:00 | Arsenal vs Leeds United | 2-1 |
| 08/05/2022 | 15:00 | Leicester City vs Everton | 1-2 |
| 08/05/2022 | 15:00 | Norwich City vs West Ham United | 0-4 |
| 08/05/2022 | 17:30 | Manchester City vs Newcastle United | 5-0 |
| 22/05/2022 | 17:00 | Arsenal vs Everton | 5-1 |
| 22/05/2022 | 17:00 | Brentford vs Leeds United | 1-2 |
| 22/05/2022 | 17:00 | Brighton & Hove Albion vs West Ham United | 3-1 |
| 22/05/2022 | 17:00 | Burnley vs Newcastle United | 1-2 |
| 22/05/2022 | 17:00 | Chelsea vs Watford | 2-1 |
| 22/05/2022 | 17:00 | Crystal Palace vs Manchester United | 1-0 |
| 22/05/2022 | 17:00 | Leicester City vs Southampton | 4-1 |
| 22/05/2022 | 17:00 | Liverpool vs Wolverhampton Wanderers | 3-1 |
| 22/05/2022 | 17:00 | Manchester City vs Aston Villa | 3-2 |
| 22/05/2022 | 17:00 | Norwich City vs Tottenham Hotspur | 0-5 |