| 13.08.2021 | 21:00 | Brentford - Arsenal | 2:0 |
| 14.08.2021 | 13:30 | Manchester United - Leeds United | 5:1 |
| 14.08.2021 | 16:00 | Burnley - Brighton & Hove Albion | 1:2 |
| 14.08.2021 | 16:00 | Chelsea - Crystal Palace | 3:0 |
| 14.08.2021 | 16:00 | Everton - Southampton | 3:1 |
| 14.08.2021 | 16:00 | Leicester City - Wolverhampton Wanderers | 1:0 |
| 14.08.2021 | 16:00 | Watford - Aston Villa | 3:2 |
| 14.08.2021 | 18:30 | Norwich City - Liverpool | 0:3 |
| 15.08.2021 | 15:00 | Newcastle United - West Ham United | 2:4 |
| 15.08.2021 | 17:30 | Tottenham Hotspur - Manchester City | 1:0 |
| 21.08.2021 | 13:30 | Liverpool - Burnley | 2:0 |
| 21.08.2021 | 16:00 | Aston Villa - Newcastle United | 2:0 |
| 21.08.2021 | 16:00 | Crystal Palace - Brentford | 0:0 |
| 21.08.2021 | 16:00 | Leeds United - Everton | 2:2 |
| 21.08.2021 | 16:00 | Manchester City - Norwich City | 5:0 |
| 21.08.2021 | 18:30 | Brighton & Hove Albion - Watford | 2:0 |
| 22.08.2021 | 15:00 | Southampton - Manchester United | 1:1 |
| 22.08.2021 | 15:00 | Wolverhampton Wanderers - Tottenham Hotspur | 0:1 |
| 22.08.2021 | 17:30 | Arsenal - Chelsea | 0:2 |
| 23.08.2021 | 21:00 | West Ham United - Leicester City | 4:1 |
| 28.08.2021 | 13:30 | Manchester City - Arsenal | 5:0 |
| 28.08.2021 | 16:00 | Aston Villa - Brentford | 1:1 |
| 28.08.2021 | 16:00 | Brighton & Hove Albion - Everton | 0:2 |
| 28.08.2021 | 16:00 | Newcastle United - Southampton | 2:2 |
| 28.08.2021 | 16:00 | Norwich City - Leicester City | 1:2 |
| 28.08.2021 | 16:00 | West Ham United - Crystal Palace | 2:2 |
| 28.08.2021 | 18:30 | Liverpool - Chelsea | 1:1 |
| 29.08.2021 | 15:00 | Burnley - Leeds United | 1:1 |
| 29.08.2021 | 15:00 | Tottenham Hotspur - Watford | 1:0 |
| 29.08.2021 | 17:30 | Wolverhampton Wanderers - Manchester United | 0:1 |
| 11.09.2021 | 13:30 | Crystal Palace - Tottenham Hotspur | 3:0 |
| 11.09.2021 | 16:00 | Arsenal - Norwich City | 1:0 |
| 11.09.2021 | 16:00 | Brentford - Brighton & Hove Albion | 0:1 |
| 11.09.2021 | 16:00 | Leicester City - Manchester City | 0:1 |
| 11.09.2021 | 16:00 | Manchester United - Newcastle United | 4:1 |
| 11.09.2021 | 16:00 | Southampton - West Ham United | 0:0 |
| 11.09.2021 | 16:00 | Watford - Wolverhampton Wanderers | 0:2 |
| 11.09.2021 | 18:30 | Chelsea - Aston Villa | 3:0 |
| 12.09.2021 | 17:30 | Leeds United - Liverpool | 0:3 |
| 13.09.2021 | 21:00 | Everton - Burnley | 3:1 |
| 17.09.2021 | 21:00 | Newcastle United - Leeds United | 1:1 |
| 18.09.2021 | 13:30 | Wolverhampton Wanderers - Brentford | 0:2 |
| 18.09.2021 | 16:00 | Burnley - Arsenal | 0:1 |
| 18.09.2021 | 16:00 | Liverpool - Crystal Palace | 3:0 |
| 18.09.2021 | 16:00 | Manchester City - Southampton | 0:0 |
| 18.09.2021 | 16:00 | Norwich City - Watford | 1:3 |
| 18.09.2021 | 18:30 | Aston Villa - Everton | 3:0 |
| 19.09.2021 | 15:00 | Brighton & Hove Albion - Leicester City | 2:1 |
| 19.09.2021 | 15:00 | West Ham United - Manchester United | 1:2 |
| 19.09.2021 | 17:30 | Tottenham Hotspur - Chelsea | 0:3 |
| 25.09.2021 | 13:30 | Chelsea - Manchester City | 0:1 |
| 25.09.2021 | 13:30 | Manchester United - Aston Villa | 0:1 |
| 25.09.2021 | 16:00 | Everton - Norwich City | 2:0 |
| 25.09.2021 | 16:00 | Leeds United - West Ham United | 1:2 |
| 25.09.2021 | 16:00 | Leicester City - Burnley | 2:2 |
| 25.09.2021 | 16:00 | Watford - Newcastle United | 1:1 |
| 25.09.2021 | 18:30 | Brentford - Liverpool | 3:3 |
| 26.09.2021 | 15:00 | Southampton - Wolverhampton Wanderers | 0:1 |
| 26.09.2021 | 17:30 | Arsenal - Tottenham Hotspur | 3:1 |
| 27.09.2021 | 21:00 | Crystal Palace - Brighton & Hove Albion | 1:1 |
| 02.10.2021 | 13:30 | Manchester United - Everton | 1:1 |
| 02.10.2021 | 16:00 | Burnley - Norwich City | 0:0 |
| 02.10.2021 | 16:00 | Chelsea - Southampton | 3:1 |
| 02.10.2021 | 16:00 | Leeds United - Watford | 1:0 |
| 02.10.2021 | 16:00 | Wolverhampton Wanderers - Newcastle United | 2:1 |
| 02.10.2021 | 18:30 | Brighton & Hove Albion - Arsenal | 0:0 |
| 03.10.2021 | 15:00 | Crystal Palace - Leicester City | 2:2 |
| 03.10.2021 | 15:00 | Tottenham Hotspur - Aston Villa | 2:1 |
| 03.10.2021 | 15:00 | West Ham United - Brentford | 1:2 |
| 03.10.2021 | 17:30 | Liverpool - Manchester City | 2:2 |
| 16.10.2021 | 13:30 | Watford - Liverpool | 0:5 |
| 16.10.2021 | 16:00 | Aston Villa - Wolverhampton Wanderers | 2:3 |
| 16.10.2021 | 16:00 | Leicester City - Manchester United | 4:2 |
| 16.10.2021 | 16:00 | Manchester City - Burnley | 2:0 |
| 16.10.2021 | 16:00 | Norwich City - Brighton & Hove Albion | 0:0 |
| 16.10.2021 | 16:00 | Southampton - Leeds United | 1:0 |
| 16.10.2021 | 18:30 | Brentford - Chelsea | 0:1 |
| 17.10.2021 | 15:00 | Everton - West Ham United | 0:1 |
| 17.10.2021 | 17:30 | Newcastle United - Tottenham Hotspur | 2:3 |
| 18.10.2021 | 21:00 | Arsenal - Crystal Palace | 2:2 |
| 22.10.2021 | 21:00 | Arsenal - Aston Villa | 3:1 |
| 23.10.2021 | 13:30 | Chelsea - Norwich City | 7:0 |
| 23.10.2021 | 16:00 | Crystal Palace - Newcastle United | 1:1 |
| 23.10.2021 | 16:00 | Everton - Watford | 2:5 |
| 23.10.2021 | 16:00 | Leeds United - Wolverhampton Wanderers | 1:1 |
| 23.10.2021 | 16:00 | Southampton - Burnley | 2:2 |
| 23.10.2021 | 18:30 | Brighton & Hove Albion - Manchester City | 1:4 |
| 24.10.2021 | 15:00 | Brentford - Leicester City | 1:2 |
| 24.10.2021 | 15:00 | West Ham United - Tottenham Hotspur | 1:0 |
| 24.10.2021 | 17:30 | Manchester United - Liverpool | 0:5 |
| 30.10.2021 | 13:30 | Leicester City - Arsenal | 0:2 |
| 30.10.2021 | 16:00 | Burnley - Brentford | 3:1 |
| 30.10.2021 | 16:00 | Liverpool - Brighton & Hove Albion | 2:2 |
| 30.10.2021 | 16:00 | Manchester City - Crystal Palace | 0:2 |
| 30.10.2021 | 16:00 | Newcastle United - Chelsea | 0:3 |
| 30.10.2021 | 16:00 | Watford - Southampton | 0:1 |
| 30.10.2021 | 18:30 | Tottenham Hotspur - Manchester United | 0:3 |
| 31.10.2021 | 15:00 | Norwich City - Leeds United | 1:2 |
| 31.10.2021 | 17:30 | Aston Villa - West Ham United | 1:4 |
| 01.11.2021 | 21:00 | Wolverhampton Wanderers - Everton | 2:1 |
| 05.11.2021 | 21:00 | Southampton - Aston Villa | 1:0 |
| 06.11.2021 | 13:30 | Manchester United - Manchester City | 0:2 |
| 06.11.2021 | 16:00 | Brentford - Norwich City | 1:2 |
| 06.11.2021 | 16:00 | Chelsea - Burnley | 1:1 |
| 06.11.2021 | 16:00 | Crystal Palace - Wolverhampton Wanderers | 2:0 |
| 06.11.2021 | 18:30 | Brighton & Hove Albion - Newcastle United | 1:1 |
| 07.11.2021 | 15:00 | Arsenal - Watford | 1:0 |
| 07.11.2021 | 15:00 | Everton - Tottenham Hotspur | 0:0 |
| 07.11.2021 | 15:00 | Leeds United - Leicester City | 1:1 |
| 07.11.2021 | 17:30 | West Ham United - Liverpool | 3:2 |
| 20.11.2021 | 13:30 | Leicester City - Chelsea | 0:3 |
| 20.11.2021 | 16:00 | Aston Villa - Brighton & Hove Albion | 2:0 |
| 20.11.2021 | 16:00 | Burnley - Crystal Palace | 3:3 |
| 20.11.2021 | 16:00 | Newcastle United - Brentford | 3:3 |
| 20.11.2021 | 16:00 | Norwich City - Southampton | 2:1 |
| 20.11.2021 | 16:00 | Watford - Manchester United | 4:1 |
| 20.11.2021 | 16:00 | Wolverhampton Wanderers - West Ham United | 1:0 |
| 20.11.2021 | 18:30 | Liverpool - Arsenal | 4:0 |
| 21.11.2021 | 15:00 | Manchester City - Everton | 3:0 |
| 21.11.2021 | 17:30 | Tottenham Hotspur - Leeds United | 2:1 |
| 27.11.2021 | 13:30 | Arsenal - Newcastle United | 2:0 |
| 27.11.2021 | 16:00 | Crystal Palace - Aston Villa | 1:2 |
| 27.11.2021 | 16:00 | Liverpool - Southampton | 4:0 |
| 27.11.2021 | 16:00 | Norwich City - Wolverhampton Wanderers | 0:0 |
| 27.11.2021 | 18:30 | Brighton & Hove Albion - Leeds United | 0:0 |
| 28.11.2021 | 15:00 | Brentford - Everton | 1:0 |
| 28.11.2021 | 15:00 | Leicester City - Watford | 4:2 |
| 28.11.2021 | 15:00 | Manchester City - West Ham United | 2:1 |
| 28.11.2021 | 17:30 | Chelsea - Manchester United | 1:1 |
| 23.02.2022 | 20:30 | Burnley - Tottenham Hotspur | 1:0 |
| 30.11.2021 | 20:30 | Newcastle United - Norwich City | 1:1 |
| 30.11.2021 | 21:15 | Leeds United - Crystal Palace | 1:0 |
| 01.12.2021 | 20:30 | Watford - Chelsea | 1:2 |
| 01.12.2021 | 20:30 | West Ham United - Brighton & Hove Albion | 1:1 |
| 01.12.2021 | 20:30 | Wolverhampton Wanderers - Burnley | 0:0 |
| 01.12.2021 | 20:30 | Southampton - Leicester City | 2:2 |
| 01.12.2021 | 21:15 | Aston Villa - Manchester City | 1:2 |
| 01.12.2021 | 21:15 | Everton - Liverpool | 1:4 |
| 02.12.2021 | 20:30 | Tottenham Hotspur - Brentford | 2:0 |
| 02.12.2021 | 21:15 | Manchester United - Arsenal | 3:2 |
| 04.12.2021 | 13:30 | West Ham United - Chelsea | 3:2 |
| 04.12.2021 | 16:00 | Newcastle United - Burnley | 1:0 |
| 04.12.2021 | 16:00 | Southampton - Brighton & Hove Albion | 1:1 |
| 04.12.2021 | 16:00 | Wolverhampton Wanderers - Liverpool | 0:1 |
| 04.12.2021 | 18:30 | Watford - Manchester City | 1:3 |
| 05.12.2021 | 15:00 | Leeds United - Brentford | 2:2 |
| 05.12.2021 | 15:00 | Manchester United - Crystal Palace | 1:0 |
| 05.12.2021 | 15:00 | Tottenham Hotspur - Norwich City | 3:0 |
| 05.12.2021 | 17:30 | Aston Villa - Leicester City | 2:1 |
| 06.12.2021 | 21:00 | Everton - Arsenal | 2:1 |
| 10.12.2021 | 21:00 | Brentford - Watford | 2:1 |
| 11.12.2021 | 13:30 | Manchester City - Wolverhampton Wanderers | 1:0 |
| 11.12.2021 | 16:00 | Arsenal - Southampton | 3:0 |
| 11.12.2021 | 16:00 | Chelsea - Leeds United | 3:2 |
| 11.12.2021 | 16:00 | Liverpool - Aston Villa | 1:0 |
| 11.12.2021 | 18:30 | Norwich City - Manchester United | 0:1 |
| 12.12.2021 | 15:00 | Burnley - West Ham United | 0:0 |
| 12.12.2021 | 15:00 | Leicester City - Newcastle United | 4:0 |
| 12.12.2021 | 17:30 | Crystal Palace - Everton | 3:1 |
| 16.03.2022 | 20:30 | Brighton & Hove Albion - Tottenham Hotspur | 0:2 |
| 14.12.2021 | 20:45 | Norwich City - Aston Villa | 0:2 |
| 14.12.2021 | 21:00 | Manchester City - Leeds United | 7:0 |
| 15.12.2021 | 20:30 | Brighton & Hove Albion - Wolverhampton Wanderers | 0:1 |
| 15.12.2021 | 20:30 | Crystal Palace - Southampton | 2:2 |
| 15.12.2021 | 21:00 | Arsenal - West Ham United | 2:0 |
| 16.12.2021 | 20:45 | Chelsea - Everton | 1:1 |
| 16.12.2021 | 21:00 | Liverpool - Newcastle United | 3:1 |
| 19.01.2022 | 20:30 | Leicester City - Tottenham Hotspur | 2:3 |
| 19.01.2022 | 21:00 | Brentford - Manchester United | 1:3 |
| 05.02.2022 | 19:00 | Burnley - Watford | 0:0 |
| 18.12.2021 | 18:30 | Leeds United - Arsenal | 1:4 |
| 19.12.2021 | 15:00 | Newcastle United - Manchester City | 0:4 |
| 19.12.2021 | 15:00 | Wolverhampton Wanderers - Chelsea | 0:0 |
| 19.12.2021 | 17:30 | Tottenham Hotspur - Liverpool | 2:2 |
| 11.01.2022 | 20:45 | Southampton - Brentford | 4:1 |
| 12.01.2022 | 20:45 | West Ham United - Norwich City | 2:0 |
| 15.02.2022 | 21:15 | Manchester United - Brighton & Hove Albion | 2:0 |
| 23.02.2022 | 20:30 | Watford - Crystal Palace | 1:4 |
| 20.04.2022 | 20:45 | Everton - Leicester City | 1:1 |
| 19.05.2022 | 21:00 | Aston Villa - Burnley | 1:1 |
| 26.12.2021 | 16:00 | Manchester City - Leicester City | 6:3 |
| 26.12.2021 | 16:00 | Norwich City - Arsenal | 0:5 |
| 26.12.2021 | 16:00 | Tottenham Hotspur - Crystal Palace | 3:0 |
| 26.12.2021 | 16:00 | West Ham United - Southampton | 2:3 |
| 26.12.2021 | 18:30 | Aston Villa - Chelsea | 1:3 |
| 26.12.2021 | 21:00 | Brighton & Hove Albion - Brentford | 2:0 |
| 27.12.2021 | 21:00 | Newcastle United - Manchester United | 1:1 |
| 23.02.2022 | 20:45 | Liverpool - Leeds United | 6:0 |
| 10.03.2022 | 20:30 | Wolverhampton Wanderers - Watford | 4:0 |
| 06.04.2022 | 20:30 | Burnley - Everton | 3:2 |
| 28.12.2021 | 16:00 | Crystal Palace - Norwich City | 3:0 |
| 28.12.2021 | 16:00 | Southampton - Tottenham Hotspur | 1:1 |
| 28.12.2021 | 16:00 | Watford - West Ham United | 1:4 |
| 28.12.2021 | 21:00 | Leicester City - Liverpool | 1:0 |
| 29.12.2021 | 20:30 | Chelsea - Brighton & Hove Albion | 1:1 |
| 29.12.2021 | 21:15 | Brentford - Manchester City | 0:1 |
| 30.12.2021 | 21:15 | Manchester United - Burnley | 3:1 |
| 24.02.2022 | 20:45 | Arsenal - Wolverhampton Wanderers | 2:1 |
| 10.03.2022 | 20:45 | Leeds United - Aston Villa | 0:3 |
| 17.03.2022 | 20:45 | Everton - Newcastle United | 1:0 |
| 01.01.2022 | 13:30 | Arsenal - Manchester City | 1:2 |
| 01.01.2022 | 16:00 | Watford - Tottenham Hotspur | 0:1 |
| 01.01.2022 | 18:30 | Crystal Palace - West Ham United | 2:3 |
| 02.01.2022 | 15:00 | Brentford - Aston Villa | 2:1 |
| 02.01.2022 | 15:00 | Everton - Brighton & Hove Albion | 2:3 |
| 02.01.2022 | 15:00 | Leeds United - Burnley | 3:1 |
| 02.01.2022 | 17:30 | Chelsea - Liverpool | 2:2 |
| 03.01.2022 | 18:30 | Manchester United - Wolverhampton Wanderers | 0:1 |
| 10.03.2022 | 20:30 | Southampton - Newcastle United | 1:2 |
| 11.05.2022 | 20:45 | Leicester City - Norwich City | 3:0 |
| 14.01.2022 | 21:00 | Brighton & Hove Albion - Crystal Palace | 1:1 |
| 15.01.2022 | 13:30 | Manchester City - Chelsea | 1:0 |
| 15.01.2022 | 16:00 | Newcastle United - Watford | 1:1 |
| 15.01.2022 | 16:00 | Norwich City - Everton | 2:1 |
| 15.01.2022 | 16:00 | Wolverhampton Wanderers - Southampton | 3:1 |
| 15.01.2022 | 18:30 | Aston Villa - Manchester United | 2:2 |
| 16.01.2022 | 15:00 | Liverpool - Brentford | 3:0 |
| 16.01.2022 | 15:00 | West Ham United - Leeds United | 2:3 |
| 01.03.2022 | 20:45 | Burnley - Leicester City | 0:2 |
| 12.05.2022 | 20:45 | Tottenham Hotspur - Arsenal | 3:0 |
| 18.01.2022 | 21:00 | Brighton & Hove Albion - Chelsea | 1:1 |
| 08.02.2022 | 20:45 | West Ham United - Watford | 1:0 |
| 08.02.2022 | 20:45 | Newcastle United - Everton | 3:1 |
| 08.02.2022 | 21:00 | Burnley - Manchester United | 1:1 |
| 09.02.2022 | 20:45 | Norwich City - Crystal Palace | 1:1 |
| 09.02.2022 | 20:45 | Tottenham Hotspur - Southampton | 2:3 |
| 09.02.2022 | 20:45 | Manchester City - Brentford | 2:0 |
| 09.02.2022 | 21:00 | Aston Villa - Leeds United | 3:3 |
| 10.02.2022 | 20:45 | Wolverhampton Wanderers - Arsenal | 0:1 |
| 10.02.2022 | 20:45 | Liverpool - Leicester City | 2:0 |
| 21.01.2022 | 21:00 | Watford - Norwich City | 0:3 |
| 22.01.2022 | 13:30 | Everton - Aston Villa | 0:1 |
| 22.01.2022 | 16:00 | Brentford - Wolverhampton Wanderers | 1:2 |
| 22.01.2022 | 16:00 | Leeds United - Newcastle United | 0:1 |
| 22.01.2022 | 16:00 | Manchester United - West Ham United | 1:0 |
| 22.01.2022 | 18:30 | Southampton - Manchester City | 1:1 |
| 23.01.2022 | 15:00 | Arsenal - Burnley | 0:0 |
| 23.01.2022 | 15:00 | Crystal Palace - Liverpool | 1:3 |
| 23.01.2022 | 15:00 | Leicester City - Brighton & Hove Albion | 1:1 |
| 23.01.2022 | 17:30 | Chelsea - Tottenham Hotspur | 2:0 |
| 12.02.2022 | 13:30 | Manchester United - Southampton | 1:1 |
| 12.02.2022 | 16:00 | Brentford - Crystal Palace | 0:0 |
| 12.02.2022 | 16:00 | Everton - Leeds United | 3:0 |
| 12.02.2022 | 16:00 | Watford - Brighton & Hove Albion | 0:2 |
| 12.02.2022 | 18:30 | Norwich City - Manchester City | 0:4 |
| 13.02.2022 | 15:00 | Burnley - Liverpool | 0:1 |
| 13.02.2022 | 15:00 | Newcastle United - Aston Villa | 1:0 |
| 13.02.2022 | 15:00 | Tottenham Hotspur - Wolverhampton Wanderers | 0:2 |
| 13.02.2022 | 17:30 | Leicester City - West Ham United | 2:2 |
| 20.04.2022 | 20:45 | Chelsea - Arsenal | 2:4 |
| 19.02.2022 | 13:30 | West Ham United - Newcastle United | 1:1 |
| 19.02.2022 | 16:00 | Arsenal - Brentford | 2:1 |
| 19.02.2022 | 16:00 | Aston Villa - Watford | 0:1 |
| 19.02.2022 | 16:00 | Brighton & Hove Albion - Burnley | 0:3 |
| 19.02.2022 | 16:00 | Crystal Palace - Chelsea | 0:1 |
| 19.02.2022 | 16:00 | Liverpool - Norwich City | 3:1 |
| 19.02.2022 | 16:00 | Southampton - Everton | 2:0 |
| 19.02.2022 | 18:30 | Manchester City - Tottenham Hotspur | 2:3 |
| 20.02.2022 | 15:00 | Leeds United - Manchester United | 2:4 |
| 20.02.2022 | 17:30 | Wolverhampton Wanderers - Leicester City | 2:1 |
| 25.02.2022 | 21:00 | Southampton - Norwich City | 2:0 |
| 26.02.2022 | 13:30 | Leeds United - Tottenham Hotspur | 0:4 |
| 26.02.2022 | 16:00 | Brentford - Newcastle United | 0:2 |
| 26.02.2022 | 16:00 | Crystal Palace - Burnley | 1:1 |
| 26.02.2022 | 16:00 | Manchester United - Watford | 0:0 |
| 26.02.2022 | 16:30 | Brighton & Hove Albion - Aston Villa | 0:2 |
| 26.02.2022 | 18:30 | Everton - Manchester City | 0:1 |
| 27.02.2022 | 15:00 | West Ham United - Wolverhampton Wanderers | 1:0 |
| 16.03.2022 | 21:15 | Arsenal - Liverpool | 0:2 |
| 19.05.2022 | 21:00 | Chelsea - Leicester City | 1:1 |
| 05.03.2022 | 13:30 | Leicester City - Leeds United | 1:0 |
| 05.03.2022 | 16:00 | Aston Villa - Southampton | 4:0 |
| 05.03.2022 | 16:00 | Burnley - Chelsea | 0:4 |
| 05.03.2022 | 16:00 | Newcastle United - Brighton & Hove Albion | 2:1 |
| 05.03.2022 | 16:00 | Norwich City - Brentford | 1:3 |
| 05.03.2022 | 16:00 | Wolverhampton Wanderers - Crystal Palace | 0:2 |
| 05.03.2022 | 18:30 | Liverpool - West Ham United | 1:0 |
| 06.03.2022 | 15:00 | Watford - Arsenal | 2:3 |
| 06.03.2022 | 17:30 | Manchester City - Manchester United | 4:1 |
| 07.03.2022 | 21:00 | Tottenham Hotspur - Everton | 5:0 |
| 10.03.2022 | 20:30 | Norwich City - Chelsea | 1:3 |
| 18.03.2022 | 21:00 | Wolverhampton Wanderers - Leeds United | 2:3 |
| 19.03.2022 | 13:30 | Aston Villa - Arsenal | 0:1 |
| 20.03.2022 | 15:00 | Leicester City - Brentford | 2:1 |
| 20.03.2022 | 17:30 | Tottenham Hotspur - West Ham United | 3:1 |
| 19.04.2022 | 21:00 | Liverpool - Manchester United | 4:0 |
| 20.04.2022 | 20:45 | Newcastle United - Crystal Palace | 1:0 |
| 20.04.2022 | 21:00 | Manchester City - Brighton & Hove Albion | 3:0 |
| 21.04.2022 | 20:45 | Burnley - Southampton | 2:0 |
| 11.05.2022 | 20:45 | Watford - Everton | 0:0 |
| 12.03.2022 | 13:30 | Brighton & Hove Albion - Liverpool | 0:2 |
| 12.03.2022 | 16:00 | Brentford - Burnley | 2:0 |
| 12.03.2022 | 18:30 | Manchester United - Tottenham Hotspur | 3:2 |
| 13.03.2022 | 15:00 | Chelsea - Newcastle United | 1:0 |
| 13.03.2022 | 15:00 | Everton - Wolverhampton Wanderers | 0:1 |
| 13.03.2022 | 15:00 | Leeds United - Norwich City | 2:1 |
| 13.03.2022 | 15:00 | Southampton - Watford | 1:2 |
| 13.03.2022 | 15:00 | West Ham United - Aston Villa | 2:1 |
| 13.03.2022 | 17:30 | Arsenal - Leicester City | 2:0 |
| 14.03.2022 | 21:00 | Crystal Palace - Manchester City | 0:0 |
| 02.04.2022 | 13:30 | Liverpool - Watford | 2:0 |
| 02.04.2022 | 16:00 | Brighton & Hove Albion - Norwich City | 0:0 |
| 02.04.2022 | 16:00 | Burnley - Manchester City | 0:2 |
| 02.04.2022 | 16:00 | Chelsea - Brentford | 1:4 |
| 02.04.2022 | 16:00 | Leeds United - Southampton | 1:1 |
| 02.04.2022 | 16:00 | Wolverhampton Wanderers - Aston Villa | 2:1 |
| 02.04.2022 | 18:30 | Manchester United - Leicester City | 1:1 |
| 03.04.2022 | 15:00 | West Ham United - Everton | 2:1 |
| 03.04.2022 | 17:30 | Tottenham Hotspur - Newcastle United | 5:1 |
| 04.04.2022 | 21:00 | Crystal Palace - Arsenal | 3:0 |
| 08.04.2022 | 21:00 | Newcastle United - Wolverhampton Wanderers | 1:0 |
| 09.04.2022 | 13:30 | Everton - Manchester United | 1:0 |
| 09.04.2022 | 16:00 | Arsenal - Brighton & Hove Albion | 1:2 |
| 09.04.2022 | 16:00 | Southampton - Chelsea | 0:6 |
| 09.04.2022 | 16:00 | Watford - Leeds United | 0:3 |
| 09.04.2022 | 18:30 | Aston Villa - Tottenham Hotspur | 0:4 |
| 10.04.2022 | 15:00 | Brentford - West Ham United | 2:0 |
| 10.04.2022 | 15:00 | Leicester City - Crystal Palace | 2:1 |
| 10.04.2022 | 15:00 | Norwich City - Burnley | 2:0 |
| 10.04.2022 | 17:30 | Manchester City - Liverpool | 2:2 |
| 16.04.2022 | 13:30 | Tottenham Hotspur - Brighton & Hove Albion | 0:1 |
| 16.04.2022 | 16:00 | Manchester United - Norwich City | 3:2 |
| 16.04.2022 | 16:00 | Southampton - Arsenal | 1:0 |
| 16.04.2022 | 16:00 | Watford - Brentford | 1:2 |
| 17.04.2022 | 15:15 | Newcastle United - Leicester City | 2:1 |
| 17.04.2022 | 15:15 | West Ham United - Burnley | 1:1 |
| 10.05.2022 | 21:00 | Aston Villa - Liverpool | 1:2 |
| 11.05.2022 | 20:30 | Leeds United - Chelsea | 0:3 |
| 11.05.2022 | 21:15 | Wolverhampton Wanderers - Manchester City | 1:5 |
| 19.05.2022 | 20:45 | Everton - Crystal Palace | 3:2 |
| 23.04.2022 | 13:30 | Arsenal - Manchester United | 3:1 |
| 23.04.2022 | 16:00 | Leicester City - Aston Villa | 0:0 |
| 23.04.2022 | 16:00 | Manchester City - Watford | 5:1 |
| 23.04.2022 | 16:00 | Norwich City - Newcastle United | 0:3 |
| 23.04.2022 | 18:30 | Brentford - Tottenham Hotspur | 0:0 |
| 24.04.2022 | 15:00 | Brighton & Hove Albion - Southampton | 2:2 |
| 24.04.2022 | 15:00 | Burnley - Wolverhampton Wanderers | 1:0 |
| 24.04.2022 | 15:00 | Chelsea - West Ham United | 1:0 |
| 24.04.2022 | 17:30 | Liverpool - Everton | 2:0 |
| 25.04.2022 | 21:00 | Crystal Palace - Leeds United | 0:0 |
| 28.04.2022 | 20:45 | Manchester United - Chelsea | 1:1 |
| 15.05.2022 | 13:00 | Tottenham Hotspur - Burnley | 1:0 |
| 15.05.2022 | 15:00 | Aston Villa - Crystal Palace | 1:1 |
| 15.05.2022 | 15:00 | Leeds United - Brighton & Hove Albion | 1:1 |
| 15.05.2022 | 15:00 | Watford - Leicester City | 1:5 |
| 15.05.2022 | 15:00 | West Ham United - Manchester City | 2:2 |
| 15.05.2022 | 15:00 | Wolverhampton Wanderers - Norwich City | 1:1 |
| 15.05.2022 | 17:30 | Everton - Brentford | 2:3 |
| 16.05.2022 | 21:00 | Newcastle United - Arsenal | 2:0 |
| 17.05.2022 | 20:45 | Southampton - Liverpool | 1:2 |
| 30.04.2022 | 13:30 | Newcastle United - Liverpool | 0:1 |
| 30.04.2022 | 16:00 | Aston Villa - Norwich City | 2:0 |
| 30.04.2022 | 16:00 | Southampton - Crystal Palace | 1:2 |
| 30.04.2022 | 16:00 | Watford - Burnley | 1:2 |
| 30.04.2022 | 16:00 | Wolverhampton Wanderers - Brighton & Hove Albion | 0:3 |
| 30.04.2022 | 18:30 | Leeds United - Manchester City | 0:4 |
| 01.05.2022 | 15:00 | Everton - Chelsea | 1:0 |
| 01.05.2022 | 15:00 | Tottenham Hotspur - Leicester City | 3:1 |
| 01.05.2022 | 17:30 | West Ham United - Arsenal | 1:2 |
| 02.05.2022 | 21:00 | Manchester United - Brentford | 3:0 |
| 07.05.2022 | 16:00 | Brentford - Southampton | 3:0 |
| 07.05.2022 | 16:00 | Burnley - Aston Villa | 1:3 |
| 07.05.2022 | 16:00 | Chelsea - Wolverhampton Wanderers | 2:2 |
| 07.05.2022 | 16:00 | Crystal Palace - Watford | 1:0 |
| 07.05.2022 | 18:30 | Brighton & Hove Albion - Manchester United | 4:0 |
| 07.05.2022 | 20:45 | Liverpool - Tottenham Hotspur | 1:1 |
| 08.05.2022 | 15:00 | Arsenal - Leeds United | 2:1 |
| 08.05.2022 | 15:00 | Leicester City - Everton | 1:2 |
| 08.05.2022 | 15:00 | Norwich City - West Ham United | 0:4 |
| 08.05.2022 | 17:30 | Manchester City - Newcastle United | 5:0 |
| 22.05.2022 | 17:00 | Arsenal - Everton | 5:1 |
| 22.05.2022 | 17:00 | Brentford - Leeds United | 1:2 |
| 22.05.2022 | 17:00 | Brighton & Hove Albion - West Ham United | 3:1 |
| 22.05.2022 | 17:00 | Burnley - Newcastle United | 1:2 |
| 22.05.2022 | 17:00 | Chelsea - Watford | 2:1 |
| 22.05.2022 | 17:00 | Crystal Palace - Manchester United | 1:0 |
| 22.05.2022 | 17:00 | Leicester City - Southampton | 4:1 |
| 22.05.2022 | 17:00 | Liverpool - Wolverhampton Wanderers | 3:1 |
| 22.05.2022 | 17:00 | Manchester City - Aston Villa | 3:2 |
| 22.05.2022 | 17:00 | Norwich City - Tottenham Hotspur | 0:5 |